Parkinson´s Disease Clinical Trial
Background: Studies about the effects of walking training with additional body load in
Parkinson's disease (PD) are lacking. There is evidence that the increase of body load
during treadmill walking improves reflex activity and leg extensor muscle activity, which
are impaired in subjects with PD.
Purpose: The purpose of this study was to assess the effects of treadmill walking training
with additional body load on the ground reaction forces, spatiotemporal, and kinematic
variables of the gait of subjects with moderate PD.
Design: This study was an A1-B-A2 single-case. Setting: The evaluation and the training were
conducted in a movement analysis laboratory, and at the rehabilitation unit of the
University, respectively.
Participants: Nine patients with PD (Hoehn and Yahr 2 through 3) and gait disturbances.
Interventions: Phases A1 and A2 included 6 weeks of gait training on a treadmill with 10%
increase of normal body mass. Phase B included 6 weeks of conventional physical therapy.
Measurements: Measures included the ground reaction forces, spatiotemporal, and kinematic
variables during overground walking, at baseline and after each phase.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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