Parkinson Disease Clinical Trial
Official title:
Parkinson's Disease Collaborative Study of Genetic Linkage
The purpose of this trial is to study genetic and other risk factors that may be important in the development of Parkinson's disease.
The The Parkinson's Research: The Organized Genetics Initiative, also known as PROGENI, is a
multi-center study involving 2000 people throughout North America who are affected, or
possibly affected, with Parkinson's disease (PD). The goal of the initiative is to study the
genetic and other risk factors which may be important in the development of PD.
In order to better understand the genetic factors leading to PD, researchers will study
families having 2 or more members diagnosed with PD. Using DNA samples from each
participant, researchers hope to identify genes that may cause a person to be at higher risk
for developing PD.
Each participant in the study will be asked to complete a family history questionnaire,
providing information about the history of PD in the family. Participants also will be asked
to discuss the symptoms they have experienced and their responses to PD medications. This
information will be used by study personnel to determine further eligibility for the study.
Those eligible for further participation will be asked to undergo a study visit at the site
closest to their residence, during which they will be asked to complete questionnaires
regarding PD symptoms, medical history, places of residence, occupations, mood, mental
status, and activity level. A blood sample will be drawn for DNA extraction. The study visit
will take about 2 hours.
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Observational Model: Cohort, Time Perspective: Prospective
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