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Parkinson Disease clinical trials

View clinical trials related to Parkinson Disease.

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NCT ID: NCT04834258 Completed - Parkinson Disease Clinical Trials

Effects of Walking and Respiratory Muscle Training on Pulmonary Function and Functional Exercise Capacity in PD

Start date: January 5, 2010
Phase: N/A
Study type: Interventional

The purpose of this randomised and controlled study is to investigate the effects of walking training combined with respiratory muscle training on pulmonary function, respiratory muscle strength, and functional exercise capacity.

NCT ID: NCT04833088 Completed - Stroke Clinical Trials

Exploratory Study About the Implementation of Technology in the Rehabilitation

Start date: June 10, 2021
Phase: N/A
Study type: Interventional

This qualitative study aims to identify the needs and recommendations of both patients and healthcare professionals in terms of rehabilitation technology, more specific three pre-defined user scenarios. These scenario were developed based on brainstorm sessions with healthcare professionals from the rehabilitation ward of UZ Brussel and AZ Sint-Maria Halle. The purpose of this study is to create an overview of recommendations that will be used to develop the smart devices in a later stage of the SAIRE project.

NCT ID: NCT04831281 Completed - Clinical trials for Dementia With Lewy Bodies

ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies (SHAPE Trial)

Start date: January 20, 2022
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the safety and treatment effects of fosgonimeton (ATH-1017) in subjects with Parkinson's Disease Dementia or Dementia with Lewy Bodies, with a randomized treatment duration of 26 weeks.

NCT ID: NCT04829760 Completed - Parkinson Disease Clinical Trials

The Effect of Psyllium and Wheat Bran on Body Weight in People With Parkinson's Disease and Constipation Symptoms

NRO
Start date: May 13, 2021
Phase: N/A
Study type: Interventional

This is a 10-week randomized, controlled study to compare the safety and efficacy of two common fiber supplements, psyllium and wheat bran in terms of changes in body weight, nutrition status, and bowel function in patients with Parkinson's Disease who have constipation symptoms. After a 2-week run-in period, participants will be randomized to receive 10 grams daily of psyllium, coarse wheat bran, or maltodextrin (placebo) for 8 weeks. Nutritional and neurological evaluations will be conducted at the beginning and end of the 8-week intervention period.

NCT ID: NCT04829006 Completed - Parkinson Disease Clinical Trials

Intelligibility Assessment for Parkinson's Disease

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The investigators aim at testing the efficacy of an app to measure sentence intelligibility in noise in speakers with Parkinson's disease and in healthy controls.

NCT ID: NCT04821687 Completed - Parkinson Disease Clinical Trials

A Study to Evaluate the add-on Efficacy and Safety of Opicapone 50 mg or an Extra Dose of L-DOPA 100 mg for the Treatment of Wearing-off in Patients With PD

Start date: June 17, 2021
Phase: Phase 4
Study type: Interventional

A Study to evaluate the add-on efficacy and safety of opicapone 50 mg or an extra dose of L-DOPA 100 mg for the treatment of wearing-off in patients with PD.

NCT ID: NCT04818528 Completed - Parkinson Disease Clinical Trials

Effects of CIMT in Parkinson's Disease Patients

Start date: December 28, 2020
Phase: N/A
Study type: Interventional

The purpose of the study was to determine the effects of constraint induced movement therapy on hand and arm functions in Parkinson's disease patients. It was a randomized controlled trial, conducted in physical therapy department of University of Lahore Teaching Hospital, Mayo Hospital and Lahore General Hospital. 40, male and female Parkinson's disease patients aged between 50-80 years were randomly allocated into two equal groups. In experimental group patients were treated with constraint induced movement therapy and routine physical therapy and in control group patients were treated with routine physical therapy. Patients were treated for a total of 4 weeks, 6 hours in a day. Patients were assessed using Frenchay Arm Test (FAT). SPSS 25 was used to analyze the data.

NCT ID: NCT04811066 Completed - Parkinson Disease Clinical Trials

Motor Learning and Multi-session tDCS in Parkinson's Disease

Start date: April 19, 2021
Phase: N/A
Study type: Interventional

The present study seeks to examine the efficacy of multi-session transcranial direct current stimulation applied over the primary motor cortex in people with Parkinson's disease on sequential motor learning performance.

NCT ID: NCT04803565 Completed - Parkinson Disease Clinical Trials

The Effect of Personalized Shoe Insole on the Gait of Parkinson's Disease Subjects

InsolePD
Start date: March 4, 2021
Phase: N/A
Study type: Interventional

This study aims to assess the efficacy of custom-made shoe insoles, for subjects with Parkinson's Disease (PD). To do that, a sample of PD subjects has been randomly assigned to an intervention group that will receive the custom-made insoles or a control group that will receive a sham insole without any specific manufacturing. Both groups will receive Physiotherapy and Occupational Therapy according to PD rehabilitation guidelines. The principal outcome will be the Time Up&Go test time, secondary outcomes 10 Meters Walking test speed, Berg Balance Scale score, SF12 score, and orthesis liking.

NCT ID: NCT04796246 Completed - Parkinson Disease Clinical Trials

Leap Motion Controller on the Functionality of Upper Limbs in Parkinson's Disease

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

Is treatment with the Leap Motion Controller device effective for upper limb functionality in individuals with Parkinson's Disease? The present study presents two hypotheses: True hypothesis: There is an improvement in the functionality of MMSS after intervention with virtual reality? Null hypothesis: There is no improvement in the functionality of MMSS after intervention with virtual reality? The proposed work will be characterized as a Randomized Clinical Trial, with evaluators outside the experimental groups (single-blind). The sample will be probabilistic, from individuals diagnosed with Parkinson's disease.