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Parasomnias clinical trials

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NCT ID: NCT03568045 Completed - Clinical trials for Circadian Rhythm Sleep Disorder, Unspecified

Feasibility Pilot of Bright Light in the Intensive Care Unit

Start date: December 3, 2018
Phase: N/A
Study type: Interventional

To evaluate the feasibility of providing daytime bright light in the ICU in a pilot randomized controlled trial.

NCT ID: NCT03556878 Completed - Sleep Disorder Clinical Trials

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment

Start date: July 20, 2018
Phase: N/A
Study type: Interventional

The goal is to collect pilot data on an adapted version of the Transdiagnostic Sleep and Circadian intervention (TranS-C), referred to as 'Fitted TranS-C'.

NCT ID: NCT03545048 Completed - Knee Osteoarthritis Clinical Trials

Effects of Internet / Web-based Exercises on the Population With Knee Arthritis

Knee OA
Start date: October 15, 2018
Phase: N/A
Study type: Interventional

1. To test whether internet-based exercises reduce the pain in knee OA 2. To check whether internet-based exercises improve the physical activity in the patients with knee OA. 3. To explore the correlation between sleep, knee inflammation (effusion, synovial hypertrophy or/and synovial hyper vascularity) and biomarkers of insulin resistance and knee pain.

NCT ID: NCT03532269 Completed - Sleep Disorder Clinical Trials

Validation of the Sleep Assessment Algorithm in the Medical Application Nightly

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

The Nightly medical application prototype is a potential, non-invasive class I medical device. The application has the potential to combine both diagnostic and therapeutic procedures for sleep. At home, Nightly measures the user's motion during sleep and then records the sleep pattern from the received data. The obtained data are then used for the diagnosis of sleep disorders (REM and NREM sleep). Using acoustic and visual stimulation, the application has the capability to support the natural process of falling asleep, provide a better night's sleep by minimizing sleep deprivation and nightmares, while awakening the user at the appropriate moment (during light sleep).

NCT ID: NCT03514732 Completed - Clinical trials for Sleep Disorder (Healthy Volunteers)

Study to Evaluate Improvements of the Quality of Sleep With NOVANUIT® Triple Action in Healthy Volunteers With Sleep Disorders

Start date: March 17, 2017
Phase: Phase 1
Study type: Interventional

Primary Objective: To estimate the range of improvement of NOVANUIT® triple action on sleep quality global score. Secondary Objectives: - To estimate the range of improvement of NOVANUIT® triple action on following parameters: time for getting asleep, sleep time, number of nocturnal awakening, number of nightmares, sleep quality (score from 0 to 10), and mean tiredness during the day (score from 0 to 10). - To estimate persistency of NOVANUIT® triple action effects after end of study product consumption. - To assess dependency to NOVANUIT® triple action after study product cessation. - To assess tolerance of NOVANUIT® triple action during the study.

NCT ID: NCT03501004 Completed - Parkinson's Disease Clinical Trials

The Study of Acupuncture on Vascular and Functional Neuroimaging in Parkinson's Disease Patients With Sleep Disorders

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to compare vascular and functional neurological changes of acupuncture in patients with Parkinson's Disease and Sleep Disorders. In the randomized controlled clinical trial study, patients meeting the criteria for inclusion will be randomly enrolled and divided into two groups in a 1:1 ratio: the acupuncture group and the sham acupuncture group. The intervention is going to be executed using the acupoints GV14(Dazhui)and GB20 (Fengchi).The acupuncture needles will be inserted to a depth of 0.8 to 1 cm using GV14(Dazhui)and GB20 (Fengchi) in the acupuncture group. The sham acupuncture group's needles will be inserted to a depth of 0.1 to 0.2 cm with nonacupuncture points located 0.5 cm in lateral to the real acupoint or to the right for midline points.During the study, researchers will observe changes in cerebral blood vessels and neuroimaging before and after acupuncture in the two groups. Using multimodal fusion advanced vascular-neuronal imaging techniques could evaluate the effect of acupuncture on brain blood vessels and function in patients with Parkinson's disease and Sleep Disorders and provide an objective neuroimaging basis for assessing the effectiveness of acupuncture.

NCT ID: NCT03499132 Completed - Clinical trials for Obstructive Sleep Apnea

Influence of Different Anesthetic Procedures on Sleep Disorder Breathing

Start date: March 1, 2018
Phase:
Study type: Observational

Obstructive sleep apnea (OSA) is a common form of sleep disordered breathing characterized by partial or complete upper airway obstructions during sleep. OSA is associated with major comorbidities and perioperative complications. These complications are caused not only by the OSA itself, but also by exacerbations of this syndrome during the perioperative period (1). Benzodiazepines, volatile anesthetics and opioids may lead to lower hypoxia and hypercapnia sensitivity and may cause respiratory depression (2-5). Therefore, preference of neuraxial blockades and avoidance of opioids has been suggested for patients with OSA (6). However, there is still lack of evidence to evaluate the effects of various anesthesia procedures on OSA (6,7). We hypothesize different anesthetic procedures will have different effect on OSA exacerbations in the postoperative period. Accordingly, the aim of this study is to compare the number of sleep disordered breathing episodes in the postoperative period in patients with different anesthetic procedures.

NCT ID: NCT03498560 Completed - Delirium Clinical Trials

Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium

Start date: November 1, 2018
Phase:
Study type: Observational

The investigators are performing this research study to understand the role of sleep disturbance on the incidence/severity of delirium after surgery. The investigators will study the brain using a polysomnography device (PSG), which records the brain's electrical activity during sleep.

NCT ID: NCT03490877 Completed - Atopic Dermatitis Clinical Trials

Scratch and Sleep Quantification in Atopic Dermatitis

SQUAD
Start date: July 13, 2018
Phase:
Study type: Observational

Atopic dermatitis (AD) is a chronic type of eczema affecting approximately 10% of adults and 12% of children in the US. The intense itching (pruritus) associated with AD can be significantly disruptive to sleep and quality of life for both the patients and their caregivers. AD is challenging to describe and measure. The purpose of this study is to see if we can reliably measure how much people with AD scratch and how scratching interferes with sleep and quality of life by using digital sensors, sleep studies and patient-reported information.

NCT ID: NCT03478306 Completed - Clinical trials for Diabetic Retinopathy

Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm

Start date: March 27, 2018
Phase: Phase 3
Study type: Interventional

This study evaluates the effect of melatonin 4 mg on circadian rhythm and visual function of patients with diabetes mellitus. Half of the patients will receive melatonin (arm-1) and the other half will receive placebo (arm-2), both groups in 3 weeks. After a week of washout, the patients will cross over to the other treatment arm.