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Pancreatitis, Chronic clinical trials

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NCT ID: NCT06205342 Not yet recruiting - Chronic Pain Clinical Trials

Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain

STEMCAP-1
Start date: August 1, 2024
Phase: Early Phase 1
Study type: Interventional

This protocol aims to test whether an infusion of allogeneic bone marrow-derived mesenchymal stromal cells (BM-MSCs) can reduce pain associated with chronic pancreatitis (CP) and explore potential mechanisms of MSC action.

NCT ID: NCT06178315 Recruiting - Clinical trials for Chronic Pancreatitis

EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis

EPOCH
Start date: December 7, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.

NCT ID: NCT06134024 Not yet recruiting - Clinical trials for Pancreatitis, Chronic

The Role of Double Pigtail Plastic Stents During Endoscopic Transmural Drainage of Pancreatic Fluid Collections.

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about clinical usefulness of double pigtail plastic stents during endoscopic transmural drainage of post-inflammatory pancreatic and peripancreatic fluid collections with use of lumen-apposing metal stents (LAMS). The main question it aims to answer is: Does introduction of double pigtail plastic stents through the LAMS increases efficacy and safety of endoscopic transmural drainage of post-inflammatory pancreatic and peripancreatic fluid collections?

NCT ID: NCT06092307 Recruiting - Pancreatitis Clinical Trials

SARcopenia in Patients With ChrOnic PANcreatitis: the SARCOPAN Study

SARCOPAN
Start date: April 18, 2023
Phase: N/A
Study type: Interventional

Sarcopenia is a complex multifactorial syndrome which could be present in older age (primary sarcopenia) or earlier in chronic disease (secondary sarcopenia). Evidence of the prevalence and incidence of sarcopenia in chronic pancreatitis is lacking, as well as studies which correlate sarcopenia to evolution of chronic pancreatitis.The main aim of this study is to evaluate whole body composition, sarcopenia, dynamic force tests, laboratory data at different stages of chronic pancreatitis. The accuracy of bioimpedance analysis and muscle ultrasound in the diagnosis of sarcopenia will also be assessed.

NCT ID: NCT06068426 Recruiting - Clinical trials for Chronic Pancreatitis

Incorporating Endoscopic Ultrasound and Elastography Towards Improving Outcomes of Pediatric Pancreatitis Management

Start date: September 13, 2021
Phase: N/A
Study type: Interventional

The main reason for this research study is to find out more about acute recurrent pancreatitis and chronic pancreatitis in children. There are few studies on childhood pancreatitis, so diagnosis and treatment are based on adult studies. This limits our understanding and treatment of these disorders in children. Endoscopic ultrasound (EUS) is a tool used to assess and diagnose pancreatic disease. We can use ultrasound with shear wave elastography (SWE) to measure fibrosis (scarring) of the pancreas. We can use SWE on both EUS and transabdominal ultrasound (TUS) systems. Both TUS and EUS SWE have been studied for diagnosis of chronic pancreatitis in adult patients, however they have not been studied in children. We plan to use EUS SWE and TUS SWE information in this study to help us understand pancreatitis in children. Children with pancreatitis and children without pancreatitis (controls) will be invited to participate in this study.

NCT ID: NCT06055595 Active, not recruiting - Pregnancy Related Clinical Trials

Genetic Factors and CP Pregnancy Outcomes

Start date: January 2010
Phase:
Study type: Observational [Patient Registry]

To explore the impact of chronic pancreatitis (CP) susceptibility genes on pregnancy outcomes.

NCT ID: NCT06015945 Recruiting - Clinical trials for Chronic Pancreatitis

Role of Home-based Transcutaneous Electrical Acustimulation for Treatment of Pain in Patients With Chronic Pancreatitis

Start date: October 5, 2023
Phase: N/A
Study type: Interventional

This research is studying a new noninvasive device-based therapy called Transcutaneous Electrical Acustimulation (TEA) to learn about its safety and how well it works as a treatment of pain in chronic pancreatitis. The purpose of this study is to investigate the potential of TEA to treat abdominal pain in patients with chronic pancreatitis (CP). The study hypothesizes that TEA can be used as a non-pharmaceutical opioid-free approach to treat pain in chronic pancreatitis.

NCT ID: NCT06006312 Recruiting - Diabetes Mellitus Clinical Trials

Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function Tests

Start date: August 2023
Phase:
Study type: Observational

The goal of this observational study is to improve the epidemiological data of pancreatic exocrine insufficiency in China, determine the FE-1 cut-off value for the classification of PEI, and explore the characteristic differences between T3cDM and type 2 diabetes mellitus in clinical symptoms and laboratory indicators.

NCT ID: NCT05989867 Recruiting - Diabetes Mellitus Clinical Trials

Evaluation of OGTT in Patients With Post-pancreatitis Diabetes Mellitus for Diagnosis and Characterization

Start date: March 1, 2023
Phase:
Study type: Observational

To evaluate the islet function and insulin secretion pattern of post-pancreatitis diabetes mellitus by oral glucose tolerance testing, and to explore the pathophysiological characteristics of PPDM-C which provide evidence for the diagnosis of PPDM-C.

NCT ID: NCT05940987 Not yet recruiting - Clinical trials for Pancreatitis, Chronic

Phone-based Smoking Cessation Intervention for Patients With Chronic Pancreatitis.(START)

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

This study aims to explore whether regular telephone intervention in patients with chronic pancreatitis can improve their smoking cessation rate.