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EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis — EPOCH  

Chronic Pancreatitis Clinical Trial

Official title:
Randomized Trial of EUS-guided Celiac Plexus Block vs. Sham for Palliation of Pain in Chronic Pancreatitis

Clinical Trial Summary

The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.

Clinical Trial Description

Chronic pancreatitis is a complex fibroinflammatory disease arising from numerous etiological factors and a variety of clinical manifestations. Abdominal pain is the most debilitating complication and can result in significant morbidity and impact on quality of life. Endoscopic ultrasonography (EUS) has been increasingly utilized for celiac plexus block (EUS-CPB), whereby a steroid in combination with a local anesthetic agent are injected into the celiac plexus within the abdominal cavity. The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06178315
Study type Interventional
Source Orlando Health, Inc.
Contact Charles Melbern Wilcox, MD
Phone 321-841-2431
Email Charles.Wilcox@orlandohealth.com
Status Recruiting
Phase N/A
Start date December 7, 2023
Completion date December 31, 2026
View Details
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