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Clinical Trial Summary

This is a cross-sectional investigation into modulating mechanisms in patients with chronic subjective tinnitus, which will compare 4 patient groups namely chronic tinnitus with chronic pain, chronic tinnitus without chronic pain, chronic pain without tinnitus and healthy controls.

Clinical Trial Description

The aim is to investigate differences in signs of central sensitization in patients with chronic subjective tinnitus and the comparison with patients suffering from both chronic subjective tinnitus and chronic musculoskeletal pain, chronic musculoskeletal pain alone and healthy controls. It can be hypothesized that central sensitization is higher in patients with chronic pain and in patients with chronic tinnitus, compared to healthy controls. Central sensitization is expected to be most present in patients with both chronic subjective tinnitus and chronic pain. Assessments of patients suffering from chronic tinnitus alone, chronic tinnitus combined with chronic pain, chronic neck pain patients without tinnitus & healthy controls: 1. Clinical measure of central sensitization: Self-perceived symptoms of central sensitization The central sensitization inventory is a self-report questionnaire that assesses clinical symptoms indicative for central sensitization. 2. Objective measures of central sensitization: Quantitative Sensory Testing Quantitative Sensory Testing (QST) is a psychophysiological assessment of sensory pathways including mechanicaldetection and pain thresholds, cutaneous heat detection and pain thresholds, and endogenous pain facilitation and inhibition. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05186259
Study type Interventional
Source University Ghent
Contact Kayleigh De Meulemeester
Phone 09 332 53 74
Email [email protected]
Status Recruiting
Phase N/A
Start date December 21, 2020
Completion date December 31, 2025

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