Pain Clinical Trial
Official title:
Lidocaine Compared to Magnesium Sulfate to Prolong Spinal Anesthesia: Non-inferiority Randomized Clinical Trial
This study evaluates the addition of continuous infusion of lidocaine or continuous infusion of magnesium sufate in the duration of spinal anesthesia.
Both lidocaine and magnesium sulfate have been shown to prolong spinal anesthesia.
The number of studies using magnesium sulfate to improve spinal anesthesia is greater than
the number of studies using lidocaine, and methodology varies significantly between studies.
Adverse effects of lidocaine are different from magnesium sulfate's. Lidocaine has a wider
therapeutic interval with fewer side effects, including: Drowsiness, Feeling Anxious, Feeling
Cold, Nervous, Numbness And Tingling, Signs And Symptoms At Injection Site, Twitching.
Magnesium sulfate's side effects include: heart disturbances, breathing difficulties, poor
reflexes, confusion, weakness, flushing (warmth, redness, or tingly feeling), sweating,
lowered blood pressure, feeling like you might pass out, anxiety, cold feeling, extreme
drowsiness, muscle tightness or contraction, or headache.
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