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Study of Opioid Rotation Versus Opioid Escalation in Patients With Moderate to Severe Cancer Pain

Pain Clinical Trial

Official title:
Efficacy and Safety of Opioid Rotation Compared With Opioid Dose Escalation in Patients With Moderate to Severe Cancer Pain - Open Label, Randomized, Prospective Study

Clinical Trial Summary

Although opioid rotation is well known treatment modality in reducing pain and opioid-induced neurotoxicity, it is not established whether opioid rotation is more appropriate or opioid escalation is more effective in controlling significant pain in cancer patients under opioid medication.

- The purpose of this study is to determine effective therapy out of opioid rotation and opioid dose escalation in patients with moderate to severe cancer pain who have been already treated with strong opioid.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02084355
Study type Interventional
Source Gyeongsang National University Hospital
Contact Se-Il Go, M.D.
Phone +82 55 750 9454
Email gose1@hanmail.net
Status Not yet recruiting
Phase Phase 3
Start date April 2014
Completion date January 2016
View Details
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