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NCT00956878 Clinical Trial

Cancer Pain Single Nucleotide Polymorphisms (SNPs)

Pain Clinical Trial

Official title:
Storage and Analysis of Patient Blood-samples for Cancer Pain Research

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00956878
Other study ID # MEC2008-166
Secondary ID
Status Completed
Phase N/A
First received August 10, 2009
Last updated December 23, 2014
Start date September 2008
Est. completion date December 2012

Study information
Verified date December 2014
Source Erasmus Medical Center
Contact n/a
Is FDA regulated No
Health authority Netherlands: Dutch Health Care Inspectorate
Study type Observational

Clinical Trial Summary

Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA. Using blood samples from clinically well-defined cancer pain patients, the investigators are going to analyze single nucleotide polymorphisms (SNPs) in genes that are known to be involved in responsiveness to opioids and sensitivity to pain.

Recruitment information / eligibility
Status Completed
Enrollment 243
Est. completion date December 2012
Est. primary completion date December 2012
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Cancer pain patients

Exclusion Criteria:

- Patients not able to provide informed consent

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Netherlands Erasmus MC, Centrumlocatie en Daniel den Hoed Rotterdam Zuid-Holland

Sponsors (1)
Lead Sponsor Collaborator
Erasmus Medical Center

Country where clinical trial is conducted

Netherlands, 

Outcome
Type Measure Description Time frame Safety issue
Primary correlation between pain SNPs and equianalgesic opioid requirement candidate SNP analysis timepoint at blood sample No
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