Pain, Postoperative Clinical Trial
Official title:
Ultrasound-guided Bilateral Erector Spinalis Plane Block on Postoperative Pain Management in Liver Transplantation Donors
| Verified date | August 2023 |
| Source | Medipol University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision. Therefore adequate analgesia is important for recovery. Erector Spinae Plane Block (ESPB) is a safe anesthesia technique used to provide postoperative analgesia. This study aimed to compare the novel ultrasound-guided ESPB technique with controls in terms of postoperative opioid consumption and postoperative pain control on donor patients.
| Status | Completed |
| Enrollment | 41 |
| Est. completion date | August 1, 2023 |
| Est. primary completion date | May 1, 2023 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 18 Years to 65 Years |
| Eligibility | Inclusion Criteria: - Donor patients scheduled for elective hepatectomy in liver transplantation surgery - ASA I-II - Patients who are aged between 18-65 Exclusion Criteria: - Patients who do not accept the procedure - Skin infection at the site of Erector Spina Plan Block area - Coagulation disorder or using anticoagulant drugs - Known local anesthetics and opioid allergy - Severe pulmonary and/or cardiovascular problems - Substance addiction or known psychiatric or mental problems - Chronic painkiller usage - Pregnancy or lactation |
| Country | Name | City | State |
|---|---|---|---|
| Turkey | Istanbul Medipol University Hospital | Istanbul |
| Lead Sponsor | Collaborator |
|---|---|
| Medipol University |
Turkey,
Chhibber A, Dziak J, Kolano J, Norton JR, Lustik S. Anesthesia care for adult live donor hepatectomy: our experiences with 100 cases. Liver Transpl. 2007 Apr;13(4):537-42. doi: 10.1002/lt.21074. — View Citation
Dewe G, Steyaert A, De Kock M, Lois F, Reding R, Forget P. Pain management in living related adult donor hepatectomy: feasibility of an evidence-based protocol in 100 consecutive donors. BMC Res Notes. 2018 Nov 26;11(1):834. doi: 10.1186/s13104-018-3941-1. — View Citation
El-Boghdadly K, Pawa A. The erector spinae plane block: plane and simple. Anaesthesia. 2017 Apr;72(4):434-438. doi: 10.1111/anae.13830. Epub 2017 Feb 11. No abstract available. — View Citation
Hacibeyoglu G, Topal A, Arican S, Kilicaslan A, Tekin A, Uzun ST. USG guided bilateral erector spinae plane block is an effective and safe postoperative analgesia method for living donor liver transplantation. J Clin Anesth. 2018 Sep;49:36-37. doi: 10.1016/j.jclinane.2018.06.003. Epub 2018 Jun 5. No abstract available. — View Citation
Tsui BCH, Fonseca A, Munshey F, McFadyen G, Caruso TJ. The erector spinae plane (ESP) block: A pooled review of 242 cases. J Clin Anesth. 2019 Mar;53:29-34. doi: 10.1016/j.jclinane.2018.09.036. Epub 2018 Oct 3. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Opioid consumption | The amount of fentanyl required by the patient and given by the device will be recorded for the first 48 hours. | Change from baseline opioid consumption at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours | |
| Secondary | Visual Analog Scale | Pain of patients will be evaluated and recorded according to the Visual Analog Scale. | Change from baseline pain scores at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours |
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