Comparison of Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block

Pain, Postoperative Clinical Trial

Official title:

Comparison of the Effects of Ultrasound-Guided Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block on Postoperative Acute Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05255562
• Other study ID #: E.Kurul-E1-22-2372
• Status: Completed
• Phase: N/A
• Start date: February 15, 2022
• Est. completion date: May 16, 2023

Study information

• Verified date: May 2023
• Source: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block, serratus anterior plane block (SAPB), and erector spinae plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In recent years, the frequency of application of plane blocks as a component of multimodal analgesia has been increased. ESPB and SAPB are some of them. There are two techniques for SAPB application. In Deep SAPB (DSAPB) application, a local anesthetic agent is given under the serratus anterior muscle. In the Superficial SAPB (SSAPB) application, the local anesthetic agent is given above the serratus anterior muscle. Since it is done by entering from the same point in two applications, it is possible to perform these two applications at the same time with a single needle entry. The mechanisms of regional analgesia techniques used after thoracic surgery operations are also different from each other. Therefore, it may be possible to obtain a more effective analgesic effect in patients by combining the mechanism of action of DSAPB and SSAPB, as in the multimodal analgesia method. This study seeks to evaluate the effect of TPVB and combined SAPB (CSAPB) after VATS.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 16, 2023
• Est. primary completion date: May 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 18 to 65 years old

• ASA physical status I-II-III

• BMI 18 to 30 kg/m2

• Elective video-assisted thoracoscopic surgery

Exclusion Criteria:

• Patient refusing the procedure

• Emergency surgery

• Chronic opioid or analgesic use

Related Conditions & MeSH terms

• Aortic Dissection
• Multimodal Analgesia
• Pain, Postoperative
• Serratus Anterior Plane Block
• Thoracic Paravertebral Block
• Thoracic Surgery, Video-Assisted

Intervention

Procedure:
• Combined Serratus Anterior Plane Block
Combined deep and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.

Drug:
• Thoracic Paravertebral Block
Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.

Locations

Country	Name	City	State
Turkey	Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital	Kecioren	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain Scores	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery.	48 hours after surgery
Secondary	Morphine Consumption	Morphine consumption for 24 hours will be recorded	24 hours after surgery