TPVB, PECSB, ESPB for Postmastectmy Pain

Pain, Postoperative Clinical Trial

— RCT  

Official title:

A Comparative Study Between Ultrasound-guided Thoracic Paravertebral Block, Pectoral Nerves Block, and Erector Spinae Block for Pain Management in Cancer Breast Surgeries. A Randomized Controlled Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05076773
• Other study ID #: 32900654326
• Status: Completed
• Phase: N/A
• Start date: April 10, 2019
• Est. completion date: August 10, 2021

Study information

• Verified date: September 2021
• Source: Menoufia University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries. The hypothesis of the study is that the three groups will give comparative results.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: August 10, 2021
• Est. primary completion date: August 10, 2021
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

1. ASA physical status classification class I or II

2. Age group 18 - 60 years of the female gender

3. Patients undergoing breast cancer surgeries

Exclusion Criteria:

1. Patient refusal

2. History of hypersensitivity to local anesthetics

3. Bleeding disorders or patients receiving anticoagulants

4. Spine or chest wall deformities

5. Pregnancy

6. Local infection at the site of injection.

Related Conditions & MeSH terms

• Pain, Postoperative

Intervention

Procedure:
• Ultrasound guided block
Giving one regional block

Drug:
• IV morphine
given when VAS>3

Locations

Country	Name	City	State
Egypt	Faculty of Medicine Menofia University	Shibin Al Kawm	Menofia

Sponsors (1)

Lead Sponsor	Collaborator
Menoufia University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).	minutes	0-24o minutess
Secondary	Postoperative pain	assessed by VAS score (0-10) where 0=no pain and 10=worst pain	48 hours
Secondary	Total morphine consumption	recorded postoperatively in mg	48 hours
Secondary	Postoperative nausea and vomiting (PONV)	4 points score of PONV (0-3) where 0=no PONV and 3=vomiting more than once	48 hours