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Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty

Pain, Postoperative Clinical Trial

Official title:
Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty, a Study of Opiate Consumption and Weight Reduction

Clinical Trial Summary

The purpose of this study is to evaluate the effects of topiramate (TPM) in obese patients with respect to weight loss and pain after total joint replacement surgery

Clinical Trial Description

Investigator hypothesize that low dose peri-operative topiramate is superior to gabapentin in reducing postoperative pain and opioid consumption after primary TJA with a more favorable side effect profile that will facilitate patient optimization via pre- and postoperative weight loss. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04613024
Study type Interventional
Source Stanford University
Contact Derek Amanatullah, Md PhD
Phone 6507232257
Email arprerna@stanford.edu
Status Not yet recruiting
Phase Early Phase 1
Start date July 1, 2023
Completion date July 1, 2025
View Details
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