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Clinical Trial Summary

The aim is to analyze the effect of intravenous lidocaine administration on postoperative opioid use in patients undergoing upper abdominal cancer surgery. Specifically, those patients undergoing gastric cancer surgery and liver cancer surgery using a laparoscopic approach


Clinical Trial Description

In a recent Cochrane Library review, despite the apparent positive results reported by intravenous administration of lidocaine as a perioperative analgesic adjuvant, the quality of the evidence is low, since the studies carried out to date present small samples, great variability in the designs and different surgical techniques studied. More studies will be needed to help improve the grade and quality of evidence in the management of acute postoperative pain and its role in opioid sparing, an especially beneficial effect in tumor pathology For this reason, the investigators have designed a randomized, double-blind, phase IV clinical trial with two treatment arms, parallel groups, in which 96 patients who underwent liver and gastric cancer surgery through laparoscopic approach participated. This study will include 2 different population groups: patients undergoing liver cancer surgery and patients undergoing gastric cancer surgery ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04584749
Study type Interventional
Source Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Contact Cristina Martinez, student PhD
Phone 34972940200
Email cmartinez@idibgi.org
Status Recruiting
Phase Phase 4
Start date November 16, 2020
Completion date December 1, 2024

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