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Effect of the Peri-incisional Multimodal Cocktail Infiltration on Postcraniotomy Headache

Pain, Postoperative Clinical Trial

Official title:
Effect of the Peri-incisional Multimodal Cocktail Infiltration on Postcraniotomy Headache

Clinical Trial Summary

Postcraniotomy headache (PCH) has been underestimated for the past decades. However, current treatments for PCH are either considered insufficient or accompanied by severe side-effects. Some studies revealed that peri-incisional injection of a mixed cocktail that contains ropivacaine, epinephrine, ketorolac, and methylprednisolone showed significant efficacy in relieving postoperative pain after total hip or knee arthroplasty. Previous literature reported that the cause of PCH was related to incision of the scalp and dura, which is considered similar to causes to postoperative pain after total hip or knee arthroplasty. Thus, investigators suppose that the cocktail mixture can better relieve PCH in adults.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03915639
Study type Interventional
Source Beijing Tiantan Hospital
Contact Fang Luo
Phone +86 13611326978
Email 13611326978@163.com
Status Not yet recruiting
Phase N/A
Start date April 2022
Completion date December 2023
View Details
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