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Postoperative Pain Control & Relief in Neonates — POPCORN  

Pain, Postoperative Clinical Trial

Official title:
Postoperative Pain Control & Relief in Neonates

Clinical Trial Summary

Pain control for newborns has made significant improvements over the last 30 years. The use of narcotics remains the standard of care for neonates undergoing minor and major surgeries. Narcotics, however, are associated with adverse effects such as respiratory depression, prolonged intubation and withdrawal symptoms. Acetaminophen (Tylenol©) has been proposed as an adjunct to reduce narcotic use but current evidence from well designed studies in newborns and premature infants is limited. This study will randomly assign neonates undergoing a surgery to either morphine plus acetaminophen or morphine alone for pain control. The subjects will be followed for 72 hours after the operation and evaluate the benefits of acetaminophen for pain control.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03677830
Study type Interventional
Source St. Louis University
Contact
Status Terminated
Phase Phase 4
Start date April 19, 2019
Completion date March 7, 2024
View Details
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