Pain, Postoperative Clinical Trial
Official title:
Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions: a Prospective Study
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
Postoperative pain is a world wide problem related with surgery. Multimodal analgesia may
include ketamine, aimed to decrease opioid adverse effects in postoperative analgesia for
major surgery, and risk of chronic postsurgical pain. Ketamine has shown efficacy as adjuvant
in multimodal analgesia, however, neuropsychiatric and cardiovascular effects of ketamine at
low doses in continue postoperative infusion are less known. This type of adverse effects may
compromise appropriated recovery.
Objective
to determine frequency of delirium, agitation, sedation, hallucinations, bad dreams and
cardiovascular changes associated with ketamine analgesic infusion treatment for
postoperative pain.
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