Pain, Postoperative Clinical Trial
Official title:
The Effect of Preemptive Sphenopalatine Ganglion Block on Anesthetic Requirements, Postoperative Pain and Functional Patient Outcomes After Functional Endoscopic Sinus Surgery
The aim of the study is to quantify postoperative pain after functional endoscopic sinus surgery (FESS) and investigate whether preemptive analgesia may positively impact intraoperative anesthetic management, decrease patient postoperative pain and discomfort, and improve patient functional outcomes.
The sphenopalatine ganglion block (SPGB) with local anesthetic is used to treat facial pain
and headache of various etiologies and has been widely used during functional endoscopic
sinus surgery (FESS). The purpose of this study was to investigate whether preemptive SPGB
may positively impact postoperative pain and functional outcomes after FESS.
A prospective, double-blind randomized placebo-controlled study was performed. 60 patients
(18 to 70 yrs), undergoing general anesthesia for bilateral FESS, were randomly assigned to
receive SPGB with either 2 ml 0.25% bupivacaine with epinephrine 1:100,000 (BP, treatment
group) or normal saline (NS, control group). SPGB was performed preemptively 10 min before
the start of surgery. Pre- and post operative (day#0, day#7, day#30) visual analogue pain
scale, SNOT-20, CT & Endoscopic scores were compared between the two groups.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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