Pain, Postoperative Clinical Trial
Official title:
Evaluation of the Effects of Conditioning of Insufflated Gas on the Core Temperature and the Post-operative Pain During Laparoscopic Surgery
During laparoscopy, administration of cold and dry carbon dioxide (CO2) leads to
hypothermia. Different types of gas conditioning have been studied in order to prevent this
specific hypothermia. Intra-abdominal administration of local anesthetics has also been
studied in order to prevent post-operative pain. In both cases, some results have been
described.
The investigators propose to evaluate in a prospective, randomized, double blind trial, the
impact of 4 different types of conditioning of insufflated gas during laparoscopy for womb
surgery on hypothermia prevention and post-operative pain. These 4 types of gas conditioning
are:
- CO2 wet and cold with nebulized Nacl and direct intra-abdominal administration of Nacl
- CO2 wet and cold with nebulized ropivacaïne 0.75% and direct intra-abdominal
administration of Nacl
- CO2 dry and cold with direct intra-abdominal administration of ropivacaïne 0.2%
- CO2 dry and cold with direct intra-abdominal administration of Nacl
The investigators use a new device (Aeroneb® Pro [Aerogen® Company]) which can wet (by
nebulization) the insufflated gas and therefore permits intraperitoneal medicament
administration (local anesthetics).
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
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