The Effects of Puberty and Weight on Sugar Metabolism in Children

Overweight Clinical Trial

Official title:

The Role of Puberty and Insulin Resistance in the Development of Hyperglucagonemia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01718080
• Other study ID #: H-29652
• Secondary ID: NIH 1K126K63691
• Status: Completed
• Phase: N/A
• First received: October 29, 2012
• Last updated: April 21, 2017
• Start date: October 2012
• Est. completion date: June 2015

Study information

• Verified date: April 2017
• Source: Baylor College of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Our goal is to investigate how hormones that control blood sugar, hunger, and stomach emptying change with puberty and being overweight. These substances change with a meal.

• For this, we need to compare lean and overweight children.

• We need to study them before and during puberty.

• All children in the study will be tested before and after a liquid meal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 83
• Est. completion date: June 2015
• Est. primary completion date: January 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 8 Years to 17 Years

Eligibility

Inclusion Criteria:

All groups:

Healthy lean and otherwise healthy overweight children and adolescents between the ages of 8 and 17.

Exclusion Criteria:

Same for all groups

The subjects will be excluded if they have:

• a history of chronic disease

• allergy to acetaminophen

• evidence or history of chemical abuse

• abnormal lab values

• pregnancy

Related Conditions & MeSH terms

• Adolescent
• Leanness
• Overweight

Locations

Country	Name	City	State
United States	Baylor College of Medicine	Houston	Texas

Sponsors (1)

Lead Sponsor	Collaborator
Baylor College of Medicine

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overweight and Lean Children Sugar Metabolism Before and During Puberty	Too much weight gain can cause changes in the substances that control blood sugar and hunger in the body. Scientists need to compare these substances in lean and overweight children before and during puberty. These substances can be measured before and after a meal in the blood and in the urine. The way your stomach moves food can change your sugar levels. We want to understand how diabetes develops by studying these things. This can help find better ways to prevent and treat diabetes.	4 hours