High-Intensity Interval Training and Fat Mass Losses

Overweight and Obesity Clinical Trial

— RIESLING  

Official title:

Effect of Two Isoenergetic Modes of High-Intensity Interval Training on Total and Abdominal Fat Mass Loss in Men With Overweight or Obesity.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05311800
• Other study ID #: ID-RCB 2019-A02999-48
• Status: Completed
• Phase: N/A
• Start date: September 1, 2021
• Est. completion date: July 1, 2022

Study information

• Verified date: February 2023
• Source: Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality, glycaemic control, lipid profile, inflammation, maximal aerobic capacity (VO2max) and gut microbiota composition in men with overweight or obesity.

The investigators hypothesized that both programs could decrease total, abdominal and visceral fat mass but due to differences in muscle solicitation, metabolism adaptation and blood flow, and that running could favors greater fat mass losses.

Description:

The first aim of this study was to compare two isoenergetic HIIT programs (cycling vs. running) on body composition in men with overweight or obesity.

20 men with overweight or obesity should completed HIIT program three times a week during twelve weeks.

i) High intensity interval training - BIKE (HIIE BIKE) 10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s) ii) High intensity interval training - RUN (HIIE RUN) 9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s)

Body composition will be measured before and after HIIT program by Dual-energy X-ray absorptiometry (DXA).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 9
• Est. completion date: July 1, 2022
• Est. primary completion date: July 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• men (18 to 65 years old)

• with overweight or obesity (BMI > 25 kg/m2 and = 40 kg/m2)

Exclusion Criteria:

• medical contraindications to intense physical activity,

• painful joints,

• taking ß-blocker

Related Conditions & MeSH terms

• Men
• Obesity
• Overweight
• Overweight and Obesity

Intervention

Other:
• Physical activity
Comparison of HIIT mode (running vs cycling)

Locations

Country	Name	City	State
France	CREPS Auvergne Rhône-Alpes / Vichy	Bellerive-sur-Allier	Allier

Sponsors (1)

Lead Sponsor	Collaborator
Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	HIIT mode and fat mass change (g)	change of total fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison	At the first and the last training - week 1 and 12
Primary	HIIT mode and abdominal fat mass change (g)	change of abdominal fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison	At the first and the last training - week 1 and 12
Secondary	Rate of carbohydrate and lipid oxidation (g.min-1) during a sub-maximal exercise by measuring gaz exchange.	Carbohydrate and lipid oxidation rate (g.min-1) during a submaximal exercise before and after the HIIT protocol. HIIT mode comparison.	At the first and the last training - week 1 and 12