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Clinical Trial Summary

This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept efficacy of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathway. The study consists of two phases: a phase 1 dose escalation/regimen exploration phase and a phase 2 expansion phase.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05848739
Study type Interventional
Source Sapience Therapeutics
Contact Steve Kaesshaefer
Phone 9737152917
Email steve.kaesshaefer@bexonclinical.com
Status Recruiting
Phase Phase 1
Start date June 5, 2023
Completion date May 31, 2027

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