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A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies — APT-CUBE  

Non Small Cell Lung Cancer (NSCLC) Clinical Trial

Official title:
A Phase 1/2, Open-label Study of the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies

Clinical Trial Summary

This is a multi-regional, multi center, open label, first in human (FIH), dose-escalation, and dose-expansion study of AP203 to evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, pharmacodynamics, and antitumor activities of AP203 in adult patients with locally advanced or metastatic solid tumors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Carcinoma
  • Carcinoma, Squamous Cell
  • Esophageal Squamous Cell Carcinoma
  • Esophageal Squamous Cell Carcinoma (ESCC)
  • Head and Neck Squamous Cell Carcinoma (HNSCC)
  • Locally Advanced or Metastatic Solid Tumors
  • Non Small Cell Lung Cancer (NSCLC)
  • Squamous Cell Carcinoma of Head and Neck
Clinical Trial Details
NCT number NCT05473156
Study type Interventional
Source AP Biosciences Inc.
Contact
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date February 2023
Completion date December 2027
View Details
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