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Clinical Trial Summary

The purpose of the trial is to determine the maximum tolerated dose and to establish the safety profile of HuMax-AXL-ADC in a mixed population of patients with specified solid tumors


Clinical Trial Description

The trial consists of two parts; a dose escalation part (phase I, first in-human (FIH)) and an expansion part (phase IIa). The dose escalation part has 2 dosing schedules: 1 dose every 3 weeks (1Q3W) dose regimen, and 3 doses every 4 weeks (3Q4W) dosing regimen. The Expansion part of the trial will further explore the recommended phase 2 dose and dosing regimens of HuMax-AXL-ADC as determined in dose escalation part. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02988817
Study type Interventional
Source Genmab
Contact
Status Completed
Phase Phase 1/Phase 2
Start date November 23, 2016
Completion date November 12, 2021

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