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Clinical Trial Summary

This is a dose optimisation study in healthy adults aged 18-30 who will be experimentally inoculated with SARS-CoV-2. The aim is to cause PCR-confirmed upper respiratory infection in the majority of challenged individuals with minimal or no illness, providing data on the course of COVID-19 and the immune response to SARS-CoV-2 infection. This will establish an optimised dose and study design that will then be used to evaluate the efficacy of treatment and vaccine candidates plus level and duration of immune protection in follow-on trials.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04865237
Study type Interventional
Source Imperial College London
Contact
Status Enrolling by invitation
Phase N/A
Start date March 6, 2021
Completion date June 3, 2022

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