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Effect of Vancomycin After Catheter Replacement — VanCat  

Central Line-associated Bloodstream Infection (CLABSI) Clinical Trial

Official title:
Effect of Single-dose Vancomycin After Catheter Replacement for Suspected Central Line-associated Bloodstream Infection (CLABSI) on Resolution of Infection in Critically Ill Patients: A Single Center Randomized Open Label Controlled Trial

Clinical Trial Summary

Randomized controlled trial of the effect of a single-dose intravenous Vancomycin after catheter replacement for suspected central line-associated bloodstream infection on resolution of infection in critically ill patients.

Clinical Trial Description

Patients on the local intensive care unit with suspicion of central line-associated bloodstream infection will be randomized to standard of care consisting of catheter replacement and blood and catheter tip cultures and to standard of care plus a single-dose vancomycin. The effect of the intervention on resolution of humoral inflammation and negativity of blood cultures will be assessed after 48 and 96 hours. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04856878
Study type Interventional
Source University of Zurich
Contact
Status Not yet recruiting
Phase Phase 4
Start date June 1, 2021
Completion date December 31, 2024
View Details
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