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Respiratory Muscle Endurance in Obesity Hypoventilation Syndrome

Obesity Hypoventilation Syndrome (OHS) Clinical Trial

Official title:
Respiratory Muscle Endurance in Obesity Hypoventilation Syndrome; Evaluation by Incremental Load Test

Clinical Trial Summary

Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity [body mass index (BMI) ≥30 kg/m2], chronic daytime hypercapnia (PaCO2 >45 mm Hg), and sleep-apnea in the absence of other known causes of hypercapnia. Respiratory system compliance decreases and resistance increases in OHS. This causes increase in work of breathing and oxygen cost of breathing, which may result in respiratory muscle fatigue. Increase in respiratory workload and increase in resistance to respiration is expected to decrease in respiratory muscle endurance (RME) in subjects with OHS.

Clinical Trial Description

In the literature, studies evaluating RME in subjects with OHS are limited. No study has been found to evaluate RME using the incremental load test in subjects with OHS. Accordingly, it was aimed to evaluate and compare respiratory muscle endurance in subjects with OHS and a control group, and to determine factors associated with respiratory muscle endurance. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04835558
Study type Observational
Source Istanbul University
Contact
Status Completed
Phase
Start date February 5, 2018
Completion date January 24, 2019
View Details
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