Spontaneous Coronary Artery Dissection Clinical Trial
Official title:
A Multicenter Italian and Spanish Observational Registry on Patients Affected by Spontaneous Coronary Artery Dissection (SCAD)
The study will investigate the clinical features, acute management and follow up of patients affected by spontaneous coronary artery dissection
Spontaneous Coronary Artery Dissection is now being increasingly studied as it is getting
more and more relevant as a cause of ACS. Its management is currently a matter of debate due
to the absence of RCT and even the trigger events related to this kind of infarction are
still unclear. Notably, the benefits from the use of the antiplatelet medications that
prolong bleeding time for a condition whose primary pathophysiology may be an intramural
bleed are under discussion.
Hence, the targets pursued by our study may be essentially distinguished in five main points:
1. To assess the characteristics of SCAD patients highlighting the predisposing and
precipitating factors related to the acute event
2. To analyze clinical presentation and management of spontaneous coronary dissections in
terms of therapeutic approach in the acute phase (conservative therapy vs
revascularization)
3. To evaluate the incidence of SCAD recurrence and of major adverse cardiovascular events
(MACEs) at follow-up
4. To analyze the impact of a single antiplatelet therapy (SAPT) over the dual one (DAPT)
along with the impact of different P2Y12i regimens on acute and long-term prognosis
5. To evaluate impact of different angiographic SCAD type on outcome
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