Clinical Trials Logo

Clinical Trial Summary

The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its recurrence. This observational study will be prospective and retrospective in its recruitment and will collect clinical information to better understand the natural history and prognosis for SCAD.


Clinical Trial Description

Spontaneous Coronary Artery Dissection (SCAD) is an under-diagnosed cause of acute coronary syndrome (ACS), myocardial infarction (MI) and sudden cardiac arrest. The inner lining of the coronary artery splits and allows blood to seep into the adjacent layer, forming a blockage (hematoma), or the artery continues to tear, creating a flap of tissue that blocks blood flow in the artery. SCAD strikes generally healthy, younger individuals (average age 42) who do not have traditional cardiac risk factors. Warning signs of SCAD encompass the full range of ACS and MI symptoms, from vague to classic. The cause of SCAD is currently unknown and the psychosocial impact of SCAD is traumatizing. The work of the iSCAD Registry will encompass the physical and psychosocial study of SCAD. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04496687
Study type Observational [Patient Registry]
Source SCAD Alliance
Contact Esther Kim, MD, MPH
Phone 704-373-0212
Email Soo.Kim@atriumhealth.org
Status Recruiting
Phase
Start date March 8, 2019
Completion date December 31, 2025

See also
  Status Clinical Trial Phase
Recruiting NCT01967511 - Defining the Basis of Fibromuscular Dysplasia (FMD)
Enrolling by invitation NCT03876847 - Genetics of Spontaneous Coronary Artery Dissection (SCAD-INSPIRE Genetics)
Completed NCT03390998 - Angiographic and Psychosocial Evaluation of Peripartum vs. Non: SCAD
Completed NCT02799186 - The Study of the Prevalence Fibromuscular Dysplasia in Patient With Haematoma or Spontaneous Coronary Artery Dissection. N/A
Enrolling by invitation NCT01427179 - Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
Active, not recruiting NCT02188069 - Canadian SCAD Study
Recruiting NCT06323811 - Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics N/A
Recruiting NCT05699200 - A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection N/A
Recruiting NCT01429727 - The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
Recruiting NCT03607981 - Spanish Registry on Spontaneous Coronary Artery Dissection
Completed NCT04415762 - Spontaneous Coronary Artery Dissection Registry (DIssezioni Spontanee COronariche ITalian-SPAnish)
Recruiting NCT04906356 - Canadian SCAD Study
Recruiting NCT04457544 - Spontaneous Coronary Artery Dissection National Swiss Registry
Not yet recruiting NCT04850417 - Randomized Study of Beta-Blockers and Antiplatelets in Patients With Spontaneous Coronary Artery Dissection Phase 4
Withdrawn NCT03335020 - Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease Phase 1