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Glucose Variability and Cognition in Prediabetes

Depression Clinical Trial

Official title:
Relations of Glucose Variability With Cognitive Function and Functional Status Among Older Adults at Risk for Diabetes

Clinical Trial Summary

This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.

Clinical Trial Description

Type 2 diabetes (T2DM) is now widely considered a major public health epidemic. T2DM is highly prevalent worldwide, is among the leading causes of death, and is an independent risk factor for dementia and less severe forms of cognitive dysfunction. The investigators are utilizing novel technology to understand the role of variability in glucose on neurocognition and functional status among middle-aged and older adults at risk for diabetes. The central hypothesis is that even before diabetes onset, variability in glucose will be associated with worse cognitive function and lower functional status. Participants will be asked to wear a glucose monitoring device over a 10-day period in their home environment. Assessment of functional status and neurocognitive function, in addition to sociodemographic factors, health habits and mood will also occur over two study visits. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04201600
Study type Observational
Source University of Maryland, Baltimore
Contact Kathleen Simpson
Phone 4106057179
Email Kathleen.Simpson@va.gov
Status Recruiting
Phase
Start date March 1, 2022
Completion date December 31, 2024
View Details
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