Clinical Trials Logo
  1. Home
  2. Other
  3. NCT03533959

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy — POLARIS  

Coronary Artery Disease Progression Clinical Trial

Official title:
Prospective Observational Study for Lesion of Neoatherosclerosis: The Efficacy of Alirocumab for the Neoatherosclerosis Reaction Investigated by Serial Optical Coherence Tomography

Clinical Trial Summary

The aim of this study is to evaluate the efficacy of alirocumab for in-stent neoatherosclerosis by using optical coherence tomography, in comparison with standard statin therapy.

Clinical Trial Description

The investigators investigate to evaluate the efficacy of alirocumab for in-stent neoatherosclerosis. The investigators enrolled the patient who performed drug eluting stent implantation and detected in-stent neoatherosclerosis by follow up optical coherence tomography, and categorized into two group; the patients with alirocumab and rosuvastatin the investigatorsre categorized alirocumab therapy group, and the patients with rosuvastatin alone were categorized standard statin therapy group.

The investigators compare these two group for outcomes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03533959
Study type Observational
Source Kobe University
Contact Hiromasa Otake, M.D., Ph.D
Phone +81-78-382-5111
Email hotake@med.kobe-u.ac.jp
Status Recruiting
Phase
Start date December 18, 2017
Completion date December 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05462262 - Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population N/A
Not yet recruiting NCT06040073 - Natural History of Coronary Atherosclerosis
Active, not recruiting NCT03349385 - Registry of Secondary Revascularization
Recruiting NCT05860400 - Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study
Completed NCT03540381 - Relation Among HDL Functionality, Neoatherosclerosis and Target Lesion Revascularization
Recruiting NCT05783804 - Plaque Reversal With Early, Aggressive Lipid Lowering Therapy
Completed NCT03192579 - Effect of Rosuvastatin and Eicosapentaenoic Acid on Neoatherosclerosis: The LINK-IT Trial Phase 4
Completed NCT03195621 - Critical Treatment of Coronary Artery Disease N/A
Recruiting NCT05800093 - Proteomics and Genomics Combined With CT to Predict CVD
Recruiting NCT04772768 - Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease
Not yet recruiting NCT06007248 - Disease Characteristics of IR-CAD: a Case-control Study
Recruiting NCT03943459 - Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease Phase 3
Recruiting NCT03788369 - Evaluation of Effectiveness and Safety of Hybrid Coronary Revascularization