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Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title:
Comparing Gastrointestinal Tolerability and Absorption of Racemic Lipoic Acid and R-lipoic Acid in Progressive Multiple Sclerosis: a Randomized Crossover Trial

Clinical Trial Summary

This is a three-week crossover study that will compare how the body absorbs and tolerates two different forms of lipoic acid: R form and racemic form.

Clinical Trial Description

This three-week double-blind crossover trial will compare two different forms of lipoic acid (LA). Every participant will take one week of daily oral 600mg R LA, have a one week washout period without LA, and take one week of daily oral 1200mg racemic LA. The order of LA type will be determined by randomization. Blood analyses will be performed to determine which form is better absorbed and a side effects questionnaire will be completed at each visit in order to determine which form is better tolerated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03493841
Study type Interventional
Source Oregon Health and Science University
Contact
Status Completed
Phase Phase 1
Start date June 8, 2018
Completion date January 25, 2019
View Details
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