Tooth Extraction Clinical Trial
Official title:
Comparison of Octacalcium Phosphate Synthetic Bone Graft (OctoFor) and Bovine-derived Bone (Bio-Oss) for Ridge Preservation After Tooth Extraction: Open, Prospective, Non-Randomised Clinical Trial
Return to normal life and shortening rehabilitation period of patients after surgical removal
of teeth is important and urgent social problem. In this regard, higher demands for quality
of care and treatment of patients, which requires the development of new approaches to the
treatment of patients, the introduction of new technologies and the associated development of
new materials . Serious problem of contemporary oral and maxillo-facial surgery and dentistry
is augmentation of bone defects generated during the surgical treatment of diseases and
injuries of the bones. The results of surgical repair of bone defects are more dependent on
the course of the process of reparative osteogenesis. Long-term periods of clinical studies
indicate that reparative osteogenesis in posttraumatic bone defects is slow - months and
years, and in some cases no bone defects filled with bone tissue.
This project aims at addressing the preservation of bone volume in humans after tooth
extraction using biomaterials with optimum performance. The practical significance of the
project is to establish an effective tissue response and, thus, possible subsequent quality
installation of dental implants. The proposed solution is based on the scientific development
of the operative techniques, and a comparative analysis of several classes of biomaterials
(xenogenic and synthetic analogs), including the use of biological precursors of bone apatite
mineralization having osteoinductive (stimulating) properties.
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