Type 2 Diabetes Treated With Insulin Clinical Trial
Official title:
Study to Evaluate the Safety and Efficacy of PAZ320 When Added to Oral Agents or Insulin in Patients With Type 2 Diabetes Mellitus
This study is to evaluate the effect that PAZ320 has on post-prandial glucose excursions measured via continuous glucose monitoring and its adverse effect profile in humans.
In this study, the investigators seek to evaluate the effect that PAZ320 has on post-prandial glucose excursions measured via continuous glucose monitoring and its adverse effect profile in humans. Continuous glucose monitors (CGM) are minimally invasive devices that measure glucose levels in interstitial fluid. A small wire is inserted subcutaneously which transmits the ambient subcutaneous glucose concentration every 5 minutes to a wireless recorder. In usual use, the patient can see these data and graph the previous 1, 3 or 9 hours to identify trends or look back over time (ie over night). In our study, the patient will be blinded to the data so as not to confound results, as it has been noted in another study that patient's blood sugar control was better when they were able to see CGM results and modified their diet. CGM's have been shown to have clinical accuracies of 95.5-98.9% and have been used in clinical trials and found to be safe. Having the patient do a finger-stick glucose intermittently during the time they are wearing the CGM improves accuracy. ;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04522882 -
Clinical Data Collection for the Closed Loop Development for the Type 2 Diabetes Treatment - DT2_1
|
N/A | |
| Completed |
NCT04274660 -
Evaluation of Diabetes and WELLbeing Programme
|
N/A | |
| Not yet recruiting |
NCT05185518 -
Assessment of an Integrated Continuous Glucose Monitor and Insulin Injection Port in Type 2 Diabetes
|
N/A | |
| Recruiting |
NCT05893797 -
A Study of LY8888AX in Participants Using a Connected Insulin Management Platform
|
N/A | |
| Completed |
NCT02791295 -
Lifestyle Intervention in Type 2 Diabetes
|
N/A | |
| Withdrawn |
NCT04957173 -
Intensive Lifestyle Intervention in Patients With Insulin-treated Type 2 Diabetes: a Pilot Project
|
N/A | |
| Not yet recruiting |
NCT05317585 -
Continuous Glucose Monitor Use in Pregnancy
|
N/A | |
| Completed |
NCT05372471 -
Efficacy of the Digital Platform for Diabetes Care Compared to Usual Care in Patients Diagnosed With Type 2 Diabetes.
|
N/A | |
| Completed |
NCT05111301 -
Control-IQ Technology in Individuals With Type 2 Diabetes
|
N/A | |
| Recruiting |
NCT04585191 -
Reducing Treatment Risk in Older Adults With Diabetes
|
N/A | |
| Recruiting |
NCT04871438 -
Flash CONtinous Glucose Monitoring in TRansition to Outpatient: Libre for Type 2 Diabetes Mellitus (CONTROL-DM)
|
N/A | |
| Completed |
NCT06060743 -
Examining the Effect of Mobile Application on Insulin Use Perception and Self-Management
|
N/A | |
| Completed |
NCT04005261 -
C-peptide Concentrations in Type 2 Diabetes Treated With Insulin; is it Time to Revise the Treatment of Type 2 Diabetes
|
||
| Terminated |
NCT03980236 -
Feasibility of Using the Livongo-Insulia Study App for Patients With Type 2 Diabetes [Pilot Study]
|
N/A | |
| Not yet recruiting |
NCT06185296 -
The Intelligent Diabetes TelemonitoRing Using Decision Support to Treat Patients on Insulin Therapy
|
N/A | |
| Completed |
NCT03437525 -
Peer Support in Diabetes Management - Insulin Peer Support
|
N/A | |
| Active, not recruiting |
NCT03070106 -
Diabetes: Functional Medicine Approach vs. Usual Care
|
N/A | |
| Recruiting |
NCT05785832 -
A Randomized Trial Evaluating Control-IQ Technology in Adults With Type 2 Diabetes
|
N/A | |
| Recruiting |
NCT04945070 -
INSULIN THERAPY DE-INTENSIFICATION WITH iGlarLixi
|
Phase 4 | |
| Recruiting |
NCT05795439 -
The CARING Study: Creating and Restoring Health Through Nutrition Guidance
|
N/A |