Clinical Trials Logo
  1. Home
  2. Other
  3. NCT01840969
  4. Details
NCT01840969 Clinical Trial

Association of Carotid Arterial Circumferential Strain With Left Ventricular Function and Hemodynamic Compromise During Off-pump Coronary Artery Bypass Surgery

Three Vessel Coronary Artery Disease Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01840969
Other study ID # 4-2011-0467
Secondary ID
Status Completed
Phase N/A
First received April 10, 2013
Last updated April 25, 2013
Start date September 2011
Est. completion date February 2013

Study information
Verified date April 2013
Source Yonsei University
Contact n/a
Is FDA regulated No
Health authority Korea: Institutional Review Board
Study type Observational

Clinical Trial Summary

This study is aimed to evaluate the association of common carotid artery circumferential strain with the echocardiographic parameters of left ventricular function and the degree of actual hemodynamic deterioration in patients undergoing multi-vessel off-pump coronary artery bypass with preserved left ventricular ejection fraction.

Recruitment information / eligibility
Status Completed
Enrollment 96
Est. completion date February 2013
Est. primary completion date February 2013
Accepts healthy volunteers No
Gender Both
Age group 20 Years and older
Eligibility Inclusion Criteria:

1. three vessel coronary artery disease

2. sinus rhythm

Exclusion Criteria:

1. New York Heart Association functional class =3

2. known pulmonary hypertension

3. known valvular heart disease

4. serum creatinine =2.0 mg/dL

5. myocardial infarction within 1 week before the surgery

6. history of cerebral or peripheral arterial occlusive disease

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Korea, Republic of Yonsei University College of Medicine Seoul

Sponsors (1)
Lead Sponsor Collaborator
Yonsei University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary TTE parameters TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em 1 day before the surgery No
Secondary change of intraoperative hemodynamic variables TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em Carotid circumferential strain : Storage of transverse image of the right CCA at approximately 1cm proximal to the bifurcation, manual trace of luminal-intimal border and automatic tracking by frame-to-frame movement of ultrasound reflections (speckles) Hemodynamic variables: cardiac index and mixed venous oxygen saturation obtained from the pulmonary artery catheter and cardiac output monitoring devices from after induction of anesthesia, left circumflex artery grafting, and to sternum closure No