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"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"

Obesity Clinical Trial

Official title:
"Reversibility of Cardiovascular Injury With Continuous Positive Airway Pressure (CPAP) Use: Mechanisms Involved"

Clinical Trial Summary

The purpose of this study is to determine the factors that are associated with improved cardiovascular function with the use of CPAP therapy on subjects diagnosed with moderate to severe obstructive sleep apnea.

Clinical Trial Description

We will monitor non-invasively changes in arterial stiffness, cardiac mass, pulmonary pressures, endothelial function, etc. We will also assess the reversibility of these changes after only 5-7 days of not using the CPAP mask. In a subgroup of subjects we will explore changes in coronary flow response after 12 weeks of CPAP use compared with baseline. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01317329
Study type Interventional
Source University of Wisconsin, Madison
Contact
Status Completed
Phase N/A
Start date March 2011
Completion date December 2014
View Details
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