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NCT ID: NCT06134752 Enrolling by invitation - Clinical trials for Persistent Atrial Fibrillation

Electroporation for Treatment of Atrial Fibrillation

ELECTROAF
Start date: December 5, 2023
Phase: N/A
Study type: Interventional

Comparison of pulmonary vein and left atrial posterior wall isolation durability and clinical outcome between radiofrequency and pulse field ablation in patients with persistent and longstanding persistent atrial fibrillation.

NCT ID: NCT06129877 Enrolling by invitation - Gastrostomy Clinical Trials

CHAMP App Feeding Difficulties Repository

Start date: November 9, 2023
Phase:
Study type: Observational [Patient Registry]

This repository will consist of home monitoring data, videos, and images of patients with feeding difficulties for asynchronous remote patient monitoring of manually entered data sent by parents to the healthcare team using the CHAMP App for children with feeding difficulties. This information will be collected under a research protocol and this repository is for future research applications.

NCT ID: NCT06128135 Enrolling by invitation - Clinical trials for Upper Limb Amputation at the Hand

Identify the Prosthesis Users' Necessities Concerning Their Devices.

Start date: February 2024
Phase:
Study type: Observational

Despite many advances in prosthesis development, there are still some areas that need to be improved. One of them is the weight of the devices which could cause muscular fatigue in long-term use of the prosthesis and even abandonment. This study aims to identify the desired improvements in prosthetic devices from the perspective of the users, therapists, and relatives. That would be done through two kinds of questionnaires about technology acceptance.

NCT ID: NCT06117761 Enrolling by invitation - Delirium Clinical Trials

Combined Activity and Cognitive Intervention for ICU Survivors

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

This mixed-methods study comprising a 3-arm pilot RCT and a qualitative study aims to investigate the preliminary effects and feasibility of a home-based combined activity and cognitive intervention for ICU survivors (COMBAT-ICU). Adopting a 3-arm design with COMBAT-ICU, exercise and attention placebo study arms will enable us to evaluate the added effects, if any, of the novel combined intervention compared with the standard exercise-only rehabilitation strategy and attention placebo. Data triangulation from quantitative and qualitative aspects can facilitate result interpretation. The study's objectives are: 1. To evaluate the preliminary effects of the COMBAT-ICU intervention for ICU survivors on PICS, physical, mental and cognitive outcomes, HRQoL, unplanned re-hospitalisation rate, and mortality. 2. To explore the feasibility and acceptability of the COMBAT-ICU intervention and ICU survivors' intervention engagement experience. The hypothesis of the first objective is that upon completion of the COMBAT-ICU intervention, ICU survivors will have reduced PICS, improved physical function, mental health, cognition and HRQoL, and reduced unplanned readmissions and mortality compared with the exercise and attention placebo groups at post-intervention and 3 months thereafter. While the hypothesis of the second objective is that the COMBAT-ICU intervention is feasible and acceptable for ICU survivors.

NCT ID: NCT06117618 Enrolling by invitation - Sepsis Clinical Trials

Sepsis Electronic Prompting for Timely Intervention and Care for Inpatients

SEPTIC-IP
Start date: November 14, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to study systemic inflammatory response syndrome (SIRS) electronic health record (EHR) alerts for sepsis in the inpatient setting. The main question it aims to answer is: do nurse alerts, prescribing clinician alerts, or both nurse and prescribing clinician alerts improve time to sepsis treatment for patients in the inpatient setting? Nurses and prescribing clinicians will receive SIRS alerts based on the group to which the patient is randomly assigned. Researchers will compare four groups: no alerts, nurse alerts only, prescribing clinician alerts only, or both nurse and prescribing clinician alerts.

NCT ID: NCT06117605 Enrolling by invitation - Sepsis Clinical Trials

Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients

SEPTIC-ED
Start date: November 14, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to study systemic inflammatory response syndrome (SIRS) electronic health record (EHR) alerts for sepsis in the emergency department (ED). The main question it aims to answer is: do nurse alerts, prescribing clinician alerts, or both nurse and prescribing clinician alerts improve time to sepsis treatment for patients in the ED? Nurses and prescribing clinicians will receive SIRS alerts based on the group to which the patient is randomly assigned. Researchers will compare four groups: no alerts, nurse alerts only, prescribing clinician alerts only, or both nurse and prescribing clinician alerts.

NCT ID: NCT06104657 Enrolling by invitation - Clinical trials for Malignant Solid Neoplasm

Qualitative Techniques to Define Meaningful Within-Patient Change in Symptoms of Advanced Cancer Patients

Start date: May 31, 2023
Phase:
Study type: Observational

This study examines qualitative techniques in defining meaningful within patients changes in symptoms in patients with cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). This study may help researcher better understand how to interpret reports from patients about their cancer symptoms and treatment side effects.

NCT ID: NCT06097039 Enrolling by invitation - Clinical trials for Non-Alcoholic Fatty Liver Disease

Fetuin-A, a Promising Serum Biomarker for Diagnosis of Non-Alcoholic Fatty Liver Disease

NAFLD
Start date: August 1, 2023
Phase:
Study type: Observational [Patient Registry]

The work investigate the role of fetuin-A in the diagnosis and assessment of the severity of non-alcoholic fatty liver disease (NAFLD).

NCT ID: NCT06083155 Enrolling by invitation - Clinical trials for Coronary Microvascular Dysfunction

The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT)

NL-CFT
Start date: October 15, 2020
Phase:
Study type: Observational [Patient Registry]

The goal of this registry is to collect data on patients referred for clinically indicated coronary vasomotor function test (CFT) and answer different questions on prevalence, safety and outcomes. The registry is observational. Patients receive yearly online questionnaires on their anginal complaints for 5 years after their CFT.

NCT ID: NCT06069466 Enrolling by invitation - Clinical trials for Acute Respiratory Distress Syndrome

Epidemiological Characteristics and Prediction System of Acute Respiratory Distress Syndrome

Start date: October 15, 2023
Phase:
Study type: Observational

This project intends to adopt the multicenter prospective real-world study method to conduct a preliminary study on the incidence, grading, risk factors, respiratory support strategies, in-hospital mortality, 3-month mortality, 6-month mortality, 1-year mortality, quality of life, lung function and limb function recovery, cognitive function, return to work and other conditions of ARDS patients in RICU. By collecting 1,000 patients, a clinical database related to ARDS in China was established to provide essential data and ideas for promoting standardized diagnosis and treatment technology for ARDS patients and further clinical intervention research. At the same time, ARDS biobank was established in China-Japan Hospital and Xiangya Hospital to realize the integration of clinical data and sample resources, and the prediction model of ARDS survival and complications of tuberculosis clinical data and biological samples was established by using big data and AI technology.