Anti-Plaque and Anti-Gingivitis Effects of Moringa Plant Extract and Fluoride Toothpastes

Oral Disease Clinical Trial

Official title:

Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Moringa Plant Extract and Fluoride Toothpastes Among a Group of Egyptian Children: A Randomized Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05390099
• Other study ID #: Moringa toothpaste
• Status: Recruiting
• Phase: N/A
• Start date: April 1, 2022
• Est. completion date: July 7, 2022

Study information

• Verified date: May 2022
• Source: Cairo University
• Contact: marwa A elchaghaby, phd
• Phone: 01006231612
• Email: marwaaly2003[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The present study aims to assess and compare the anti-plaque and anti-gingivitis effects of Moringa plant extract and Fluoride toothpastes among a group of Egyptian Children.

Description:

In the last few years, the use of plant extracts in alternative medicine has evolved widely. Various herbal products, including mouthwash and toothpaste, are now available and have been shown to possess a beneficial effect on oral health .Moringa plant is used to treat various diseases including the treatment of the oral cavity or dentistry .

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: July 7, 2022
• Est. primary completion date: July 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 12 Years to 14 Years

Eligibility

Inclusion Criteria:

• Children of 12-14 years of age.
• Presence of gingivitis-calculus, and plaque (gingival index [GI]score =1/plaque index [PI] score =1).
• Children willing to participate.
• Children whose parents/caretakers gave informed consent. Exclusion criteria
• Children having fixed or removable orthodontic appliances or removable prostheses.
• Children suffering from any systemic illness.
• Children who were already using mouthwashes.
• History of oral prophylaxis within 6 months.
• Children using any other oral hygiene aids.

Related Conditions & MeSH terms

• Gingivitis
• Mouth Diseases
• Oral Disease

Intervention

Drug:
• Moringa oleifera leaf
Moringa toothpaste

Locations

Country	Name	City	State
Egypt	Cairo university	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	gingival index (Loe and Sillness, 1963)	index	6 weeks
Secondary	plaque index (Sillness and Loe, 1964)	index	6 weeks