Effect of Probiotic on Oral Health of Children

Status Recruiting

Clinical Trial Summary

The aim of the randomized, double-blind clinical trial with placebo is to answer the clinical question , or in children with diagnosed childhood early caries the use of L.salivarius and cranberry contained in NutroPharma lozenges will reduce new carious lesions and reduce the titre of the carcinogenic bacteria Streptococcus mutans, compared to the control group in which the placebo will be administered? The main end point will be to reduce the titre of cariogenic bacteria.

Clinical Trial Description

Probiotic bacteria are used in the prevention and treatment of gastrointestinal diseases and infections, including the treatment of oral diseases. Probiotic bacteria can be found in saliva, plaque and adhering directly to the mucous membrane. They compete with cariogenic bacteria and pathogens of periodontal disease. Increased interest in probiotics means that attempts are being made to find new solutions regarding the methods of their administration. The use of probiotic bacteria brings beneficial health effects. Lactobacillus salivarius is a strain isolated from human milk. It is inactive (heat treatment) and therefore does not produce metabolites that can promote the formation of carious lesions in the mouth by lowering the mouth potential of hydrogen. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03919838
Study type	Interventional
Source	Medical University of Warsaw
Contact
Status	Recruiting
Phase	N/A
Start date	July 19, 2019
Completion date	December 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05039320` - The Effect of Probiotics on Oral Health	N/A
Not yet recruiting	`NCT06081868` - RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda	N/A
Completed	`NCT05853679` - Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly Residents	N/A
Recruiting	`NCT04386421` - A Comparison of Three Different Modalities in Improving Oral Hygiene	Phase 4
Completed	`NCT04153266` - Oral Epithelial Dysplasia Informational Needs Questionnaire
Not yet recruiting	`NCT03679988` - Prevalence of Oral Mucosal Alterations in Mucocutaneous Ocular Disorders
Completed	`NCT06332846` - Oral Health in Patients Hospitalized Because of Ischemic Stroke
Completed	`NCT03723174` - Impact of an Educational Program on Gingival Status and Oral Health Related Quality of Life
Completed	`NCT03438045` - Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study	N/A
Completed	`NCT03123705` - El Paso Public Health Biorepository
Completed	`NCT05389124` - Metagenome Resilience in Experimental Gingivitis
Recruiting	`NCT04386460` - Covid-19 and Prevention of Malnutrition After Confinement by Dentists
Recruiting	`NCT06321003` - SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography
Recruiting	`NCT03736070` - Assessment of Routine Oral Screening Programs for New Prisoners
Recruiting	`NCT04581486` - Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia	N/A
Recruiting	`NCT05942794` - Identification of Oral Lesions Through an Autofluorescence System	N/A
Completed	`NCT02262247` - A Post-Market Clinical Trial for Access and Visualization of the Oropharynx, Hypopharynx and Larynx During Transoral Procedures	N/A
Completed	`NCT05418335` - Oral Health and Vitamin D in Stroke Patients
Enrolling by invitation	`NCT05758467` - Oral Health in Adults: Social Gradients and Correlation With Cardiovascular Health
Active, not recruiting	`NCT05439382` - Analysis of Root Coverage Stability.