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Opioid Use, Unspecified clinical trials

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NCT ID: NCT04099030 Completed - Clinical trials for Opioid Use, Unspecified

Effect of Opioid Shortage on Drug Selection

Start date: April 5, 2019
Phase:
Study type: Observational

This study will look at the effects of fentanyl shortage in laparoscopic cholecystectomy cases. The opioid shortage, specifically hydromorphone and fentanyl, caused a decrease in administration of opioid analgesia for laparoscopic cholecystectomy intraoperatively.

NCT ID: NCT04081545 Active, not recruiting - Anesthesia Clinical Trials

Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery

Start date: December 24, 2019
Phase: Phase 3
Study type: Interventional

A comparison of post-operative opioid use in laparoscopic bariatric surgery patients receiving opioid or opioid-free anesthesia.

NCT ID: NCT04069403 Completed - Health Behavior Clinical Trials

An Opioid Prescribing Nudge

OHS
Start date: September 10, 2019
Phase: N/A
Study type: Interventional

Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures. Test the impact of reports on opioid prescriber behaviors with the following primary measures: number of prescriptions with concurrent benzo within reporting period, number of prescriptions with concurrent muscle relaxants within reporting period, and number of encounters with naloxone prescriptions for patients with any opioid-related diagnosis within reporting period. Create a blueprint to implement the concurrent opioid prescribing nudge intervention in other settings.

NCT ID: NCT03959969 Completed - Clinical trials for Opioid Use, Unspecified

Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery

Start date: July 17, 2019
Phase: N/A
Study type: Interventional

This is a randomized controlled trial assessing the utility of an educational video on pain management after a cesarean section to reduce opioid use. The educational video will be shown during the patient's postpartum stay and the amount of opioid and adjunct medications will be assessed in those who watched the video compared to those who received the standard of care discharge instructions without the video. Participants will be contacted 7 and 14 days after cesarean birth (post operative day number 7 and number 14) to complete a telephone survey on their overall pain management and to determine how many opioid tablets have been used.

NCT ID: NCT03923374 Recruiting - Opioid-use Disorder Clinical Trials

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Mother/BabyOUD
Start date: September 15, 2018
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).

NCT ID: NCT03773484 Completed - Clinical trials for Opioid Use, Unspecified

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety (AESOPS): R21 Pilot Phase

AESOPS
Start date: March 25, 2019
Phase: N/A
Study type: Interventional

There is a lack of evidence that long-term opioid use offers benefit for noncancer pain and an abundance of evidence of harm. The objective of the R21 pilot phase of the Application of Economics & Social psychology to improve Opioid Prescribing Safety (AESOPS) is to develop and test novel behavioral nudges to encourage adherence to pain and CDC guidelines for opioid prescribing for persons with noncancer pain. Interventions will leverage the electronic health record (EHR) to discourage unnecessary opioid prescribing through the application of "behavioral insights"-empirically-tested social and psychological interventions that affect choice.

NCT ID: NCT02901275 Completed - Pain Clinical Trials

Enhancing Medication-based Analgesia in Humans

Start date: December 2016
Phase: Phase 2
Study type: Interventional

This is a single-group, within-subject, double-blind, double-dummy, placebo and active-controlled study evaluated whether the FDA-approved cannabinoid dronabinol (Marinol) would enhance analgesia, subjective reports, and cognitive performance when compared to the FDA-approved opioid hydromorphone (Dilaudid).

NCT ID: NCT02747875 Terminated - Clinical trials for Opioid Use, Unspecified

Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery

CV_RCT_M_F
Start date: September 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if methadone improves postoperative pain control in pediatric patient's undergoing cardiac surgery.

NCT ID: NCT02653144 Completed - Clinical trials for Opioid Use, Unspecified

the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block

Start date: March 2016
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine if perineural dexmedetomidine can provide increased prolongation of analgesia when compared to perineural dexamethasone in patients receiving regional block for shoulder surgery. If so, dexmedetomidine may serve as a superior adjunct to peripheral nerve blocks in a rapidly evolving, ambulatory-centered surgical setting.

NCT ID: NCT02483468 Completed - Clinical trials for Chronic Low Back Pain

The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back Pain

Start date: August 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the effects of cognitive-behavioral therapy in combination with transcranial direct current stimulation in (1) improving pain and functionality, (2) reducing severity of opioid use disorders, and (3) reducing impairment in associated mental health areas (e.g., depression, anxiety, PTSD, sleep). The investigators will also determine the effects of treatment on neural activity in cognitive and limbic brain regions involved in pain regulation using functional magnetic resonance imaging (fMRI), and examine its relationship to opioid use severity.