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Opioid Use, Unspecified clinical trials

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NCT ID: NCT06469177 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care

Start date: September 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain control versus standard of care. The main questions it aims to answer are: 1. Will elective shoulder, hip and knee arthroplasty patients using PainCoach App be prescribed and/or use less opioids, measured by total morphine milliequivalents (MME) after surgery when compared to those treated as standard of care while maintaining similar pain control? 2. Will arthroplasty surgeons using PainCoach App write more patient-specific prescriptions resulting in a reduction in opioids prescribed after surgery with no increase in further opioids prescribed in the months following surgery? 3. Will the use of Pain Coach App lead to equal or reduced healthcare system utilization after surgery? 4. Will patients and surgeons using PainCoach App find it helpful enough to use it again and recommend to colleagues, family and friends? Researchers will compare participants assigned to use Pain Coach App vs participants assigned to standard of care arm to see if there are differences in opioid prescriptions and self reported use. Participants will either use the Pain Coach App or follow standard of care instructions and be followed forward for the opioid prescriptions dispensed in community and self-reported opioids use at study end.

NCT ID: NCT06291363 Not yet recruiting - Anesthesia Clinical Trials

Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.

ESMONOL
Start date: April 4, 2024
Phase: Phase 4
Study type: Interventional

This study aims to evaluate esmolol's perfusion impact during induction and maintenance of general anesthesia, using Nociception-Level-guided control of nociception, in adult patients undergoing laparoscopic and lower abdominal surgery, on intraoperative remifentanil consumption and postoperative pain in the Post-Anesthesia Care Unit.

NCT ID: NCT01313247 Not yet recruiting - Advanced Cancer Clinical Trials

Paracetamol for Cancer Pain

Start date: April 2011
Phase: Phase 4
Study type: Interventional

Randomised, double-blind placebo controlled cross-over trial Main goal: Optimize the medical pain treatment for patients with advanced cancer disease Study goal: Measure paracetamol's additional analgesic effect in a situation where the patient is concomitantly treated with oral opioids eqv. morphine > 100 mg/d.