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Ocular Hypertension clinical trials

View clinical trials related to Ocular Hypertension.

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NCT ID: NCT05335122 Active, not recruiting - Ocular Hypertension Clinical Trials

A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Start date: March 16, 2022
Phase: Phase 2
Study type: Interventional

To assess efficacy, and safety of a single sustained release dose of the OTX-TIC drug product (2 travoprost dose strengths) in subjects with Open Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

NCT ID: NCT05333419 Completed - Ocular Hypertension Clinical Trials

Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension.

Start date: March 4, 2022
Phase: Phase 1
Study type: Interventional

This is an open label, single dose (100 ng/day) study to assess the safety, tolerability and biodegradation of the PA5436 Latanoprost FA SR Ocular Implant in adults who have OAG or OHT.

NCT ID: NCT05304299 Completed - Supplement Clinical Trials

Alleviating Effects Against High Intraocular Pressure by Oral Intake of Cordyceps Cicadae Mycelia

Start date: March 10, 2020
Phase: N/A
Study type: Interventional

This study will investigate the effects of lowering intraocular pressure by oral intake of Cordyceps cicadae mycelia, to provide evidence-based data for high intraocular pressure relief.

NCT ID: NCT05299593 Recruiting - Ocular Hypertension Clinical Trials

24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration.

HERO
Start date: June 4, 2020
Phase: Phase 4
Study type: Interventional

This is a phase IV, interventional, multi-center, open clinical Trial. Patients will be administered one eye drop of tafluprost/timolol fixed combination at 20:00 (+/- 1 hour), in the treatment of open angle glaucoma and ocular hypertension. The patients will suspend the treatment with latanoprost.

NCT ID: NCT05279716 Recruiting - Ocular Hypertension Clinical Trials

Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl

NOPAPS
Start date: February 15, 2022
Phase: Phase 4
Study type: Interventional

This study is for patients have been using prostaglandin analogue eye drops with a preservative for 3 months or more and have been diagnosed with prostaglandin-associated peri-orbital disease. the investigators would like to confirm the real world evidence(RWE) of safety and efficacy after changing to Eybelis ophthalmic solution 0.002%.

NCT ID: NCT05277870 Recruiting - Ocular Hypertension Clinical Trials

Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular Hypertension

Start date: February 28, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety, efficacy, and usability of an eyedrop bottle adaptor that creates smaller eyedrops, Nanodropper, in an open-angle glaucoma/ocular hypertension patient population.

NCT ID: NCT05273385 Recruiting - Glaucoma Clinical Trials

Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma

Start date: October 10, 2022
Phase: N/A
Study type: Interventional

Glaucoma is the leading cause of irreversible blindness worldwide. Previous studies demonstrate that smaller eye drops used in the treatment of glaucoma are just as efficacious as their larger counterparts. The proposed study hopes to demonstrate the non-inferiority of using Nanodropper to lower intraoccular pressure (IOP) in glaucoma patients compared to standard of care eye drops.

NCT ID: NCT05248139 Not yet recruiting - Cataract Clinical Trials

Safety and Effectiveness of Drop-free Small Incision Cataract Surgery

Start date: October 2022
Phase: N/A
Study type: Interventional

This is a randomized control trial comparing the effects of subconjunctival triamcinolone administration during surgery to topical prednisolone drops on the development of post-operative inflammation and macular edema in manual small incision cataract surgery.

NCT ID: NCT05241938 Recruiting - Ocular Hypertension Clinical Trials

PSLT Compared to Prostaglandin Analogue Eye Drops

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This study aims to compare the efficacy of PSLT and the topical use of prostaglandin-like hypotensive eye drops in the treatment of ocular hypertensive or glaucomatous patients in decreasing intraocular pressure and measuring changes in functional, structural and biomechanical parameters evaluated by computerized perimetry and optical coherence tomography (OCT) related to pressure change resulting from treatments

NCT ID: NCT05235321 Recruiting - Glaucoma Clinical Trials

Automated Applanation Tonometry

Start date: November 21, 2022
Phase: N/A
Study type: Interventional

Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability. The purpose of this study is to develop an automated and objective method for performing applanation tonometry using standard ophthalmic equipment as well as using 2 portable prototypes.