Obesity: an Underappreciate Risk Factor for Severe Form of COVID-19

Obesity Clinical Trial

Official title:

Obesity: an Underappreciate Risk Factor for Severe Form of COVID-19: Retrospective Cohort Study of 415 Cases

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05771857
• Other study ID #: Service anesthesie Reanimation
• Status: Completed
• Start date: March 1, 2020
• Est. completion date: October 1, 2021

Study information

• Verified date: March 2023
• Source: Mohammed VI University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Our study has the objective of identifying the epidemiological profil of the patients, as well as, the clinical, radiological and prognosis of obese patients with covid 19.

Description:

Introduction: COVID 19 pandemic continues to progress with a considerable mortality and morbidity throughout the world since its emergence in December 2019. Many studies were conducted to identify the predictive factors of mortality of those infected with the virus. The previous studies noticed that obesity seems to be associated with severe form of respiratory distress syndrome. Our study has the objective of identifying the epidemiological profil of the patients, as well as, the clinical, radiological and prognosis of obese patients with covid 19.

Methods: investigators led a retrospective monocentric, descriptive and analytic study, in the department of anesthesia and intensive care unit of the university hospital of Mohamed VI Oujda, in Morocco, from March 2020 to October 2021, including all the patients tested positive for the infection.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 415
• Est. completion date: October 1, 2021
• Est. primary completion date: September 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• All patients presenting an infection with SARS-CoV-2 that were hospitalized in the intensive care unit.

Exclusion Criteria:

• None

Related Conditions & MeSH terms

• COVID-19
• COVID-19 Pandemic
• Obesity

Intervention

Device:
• Obesity
the objective of identifying the epidemiological profil of the patients, as well as, the clinical, radiological and prognosis of obese patients with covid 19

Locations

Country	Name	City	State
Morocco	younes Oujidi	Berkane

Sponsors (1)

Lead Sponsor	Collaborator
Mohammed VI University Hospital

Country where clinical trial is conducted

Morocco, 

References & Publications (3)

Gao F, Zheng KI, Wang XB, Sun QF, Pan KH, Wang TY, Chen YP, Targher G, Byrne CD, George J, Zheng MH. Obesity Is a Risk Factor for Greater COVID-19 Severity. Diabetes Care. 2020 Jul;43(7):e72-e74. doi: 10.2337/dc20-0682. Epub 2020 May 14. No abstract available. — View Citation

Simonnet A, Chetboun M, Poissy J, Raverdy V, Noulette J, Duhamel A, Labreuche J, Mathieu D, Pattou F, Jourdain M; LICORN and the Lille COVID-19 and Obesity study group. High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation. Obesity (Silver Spring). 2020 Jul;28(7):1195-1199. doi: 10.1002/oby.22831. Epub 2020 Jun 10. Erratum In: Obesity (Silver Spring). 2020 Oct;28(10):1994. — View Citation

Yu W, Rohli KE, Yang S, Jia P. Impact of obesity on COVID-19 patients. J Diabetes Complications. 2021 Mar;35(3):107817. doi: 10.1016/j.jdiacomp.2020.107817. Epub 2020 Nov 26. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Obesity: An underappreciate risk factor for severe form of COVID-19: Retrospective cohort study of 415 cases	Is obesity a predictive factor of need of intensive care, in addition to the mortality of covid 19?	in all the 22 mounths
Primary	Risk factor for severe form of COVID-19	identify the epidemiological profil of the patients, as well as, the clinical, radiological and prognosis of obese patients with covid 19.	in all the 22 mounths