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Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study

Obesity Clinical Trial

Official title:
Effect of Sacubitril/Valsartan on Cardiac Function Assessed by Cardiac Magnetic Resonance (CMR) in Hypertensive Patients Stratified by Body Mass Index (BMI): A Real World Study

Clinical Trial Summary

The purpose of this study is to investigate the effect of sacubitril/valsartan on cardiac function assessed by cardiac magnetic resonance (CMR) in hypertensive patients stratified by BMI.

Clinical Trial Description

Obesity is one of the risk factors of hypertension, and affects cardiac structure and function in the long term for hypertensive patients. Sacubitril/valsartan is regarded as a better antihypertensive drug for the improvement of cardiac function for patients with heart failure, but it remains unclear whether there are differences among different BMI groups. Therefore, the aim of this study was to evaluate the benefit of sacubitril/valsartan versus other antihypertensive drugs on cardiac structure and function assessed by CMR in hypertensive patients stratified by BMI in the real world. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05498675
Study type Observational
Source Beijing Friendship Hospital
Contact Rongchong Huang, M.D.
Phone +86-13811039417
Email rchuang@ccmu.edu.cn
Status Recruiting
Phase
Start date September 1, 2021
Completion date September 1, 2024
View Details
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