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L-arginine and Asymmetric Dimethylarginine (ADMA) and Lifestyle Protocols

Obesity Clinical Trial

Official title:
The Effects of Different Acute Nutritional Protocols and Lifestyle Modification on Circulating L-arginine and Asymmetric Dimethylarginine (ADMA) in Obese and Type 2 Diabetic Subjects

Clinical Trial Summary

Low serum L-arginine (Arg) and high asymmetric dimethylarginine (ADMA) can predict microvascular complications in type 2 diabetes (T2DM). The investigators examined whether or not Arg and ADMA are affected by dietary factors or lifestyle modification in overweight/ obese and T2DM subjects.

Clinical Trial Description

The investigators tested the effects on serum Arg and ADMA of a) a single load of ingested dextrose, protein, fat or alcohol, each consumed within 10 minutes; b) a single episode of physical exercise; c) a 12 weeks lifestyle modification program comprised of a standard dietary and physical activity counseling in obese or T2DM subjects on circulating Arg and ADMA (n=43) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04406402
Study type Interventional
Source Tel-Aviv Sourasky Medical Center
Contact
Status Completed
Phase N/A
Start date December 5, 2006
Completion date December 10, 2008
View Details
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