Obesity Clinical Trial
Official title:
Hepassocin Levels in Patients With Polycystic Ovary Syndrome
Verified date | April 2020 |
Source | Gaziosmanpasa Taksim Research and Education Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The investigators aimed to investigate hepassocin levels in patients with polycystic ovary syndrome (PCOS). There are 3 groups aged between 18 and 35 years as non-obese healthy women, non-obese women with PCOS, and obese women (BMI>30) with PCOS.
Status | Completed |
Enrollment | 90 |
Est. completion date | March 25, 2020 |
Est. primary completion date | March 15, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - 60 patients with PCOS aged between 18 and 35 and age-matched 30 healthy women with BMI<30 Exclusion Criteria: Premature ovarian failure (FSH >30 mIU/mL), tumors secreting androgens, non-classical congenital adrenal hyperplasia, Cushing syndrome and irregular menses due to thyroid dysfunction (TSH >5 mIU/L ), hyperprolactinemia, more than twofold high transaminase levels (>70 U/L), patients with cigarette smoking, alcohol consumption, oral contraceptives use, medications that are affecting liver function test, insulin metabolism and lipid metabolism, patients with a history of chronic diseases such as diabetes mellitus, hypertension, chronic liver disease, chronic kidney disease, autoimmune disease, inflammatory disease, malignant disease, bleeding disorders, and thrombosis were also excluded. All the patients were beta-HCG, hepatitis B surface antigen, and hepatitis C antibody negative. - |
Country | Name | City | State |
---|---|---|---|
Turkey | Gaziosmanpasa Taksim Education and Research Hospital | Istanbul |
Lead Sponsor | Collaborator |
---|---|
Fatma ketenci gencer |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Hepassocin levels in patients with polycystic ovary syndrome | hepassocin levels should be increased in polycyctic ovary syndrome due to its relation with insulin resistance. | January 2020-March 2020 |
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