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How Does Prostate Cancer Metastasize? Studying the Role of Secreted Packages (Exosomes) From Fat Tissue in Lean and Obese Patients — EXOPRO  

Obesity Clinical Trial

Official title:
The EXOPRO Study: How Does Prostate Cancer Metastasize? Understanding the Role of Exosomal Communication in Lean vs Obese Patients

Clinical Trial Summary

The investigators will be collecting prostate and fat tissue from participants undergoing radical prostatectomy to culture and study in the laboratory.

Clinical Trial Description

Both obesity and prostate cancer are major health problems in the UK, affecting 1 in 3 and 1 in 8 men respectively. Moreover, obesity increases the risk of developing aggressive disease and the risk of prostate cancer spreading. How this happens is not known. The investigators want to understand how fat cells communicate with prostate cancer cells. Investigators will be collecting prostate and fat tissue from radical prostatectomy participants for culture, in particular to look at exosome communication. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04167722
Study type Observational
Source Imperial College London
Contact Joseph Tam, MBBCh
Phone +442075942135
Email j.tam18@imperial.ac.uk
Status Recruiting
Phase
Start date October 1, 2019
Completion date October 1, 2024
View Details
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