The Glycemic Effect of Added Sugar on Bake Beans

Obesity Clinical Trial

— GIF  

Official title:

The Glycemic Effect of Added Sugar on Bake Beans

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03868683
• Other study ID #: 2016/00926
• Status: Completed
• Phase: N/A
• Start date: August 20, 2018
• Est. completion date: April 17, 2019

Study information

• Verified date: March 2019
• Source: Clinical Nutrition Research Centre, Singapore
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.

Description:

There will be a total of 7 test session. Each session will last for 3 hours. At each test session, volunteers will be served with 7 test meals and blood will be collected. After an overnight fast, subjects will visit the research center. Two fasting capillary blood samples will be collected via fingerpick. Following the fasting samples, volunteers will consume the test meals. Further blood samples will be collected at 15, 30, 45, 60, 90, 120, 150, 180 minutes after the ingestion of test meal. These samples will be used to analyses for whole capillary blood glucose. At every 30 minute interval, samples will be collected for analysis of capillary plasma insulin.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: April 17, 2019
• Est. primary completion date: April 17, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 21 Years to 60 Years

Eligibility

Inclusion Criteria:

• Chinese ethnicity

• Age =21 and = 60 years

• Body mass index between 18.5 to 25 kg/m2

• Normal blood pressure <140/90 mmHg

• Fasting blood glucose <6.0 mmol/L

• In general good health

Exclusion Criteria:

• Current Smoker

• have any metabolic diseases (such as diabetes, hypertension etc)

• have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)

• having medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)

• have intolerances or allergies to any foods

• partake in sports at the competitive and/or endurance levels

• intentionally restrict food intake

Related Conditions & MeSH terms

• Diabetes Mellitus, Type 2
• Obesity
• PreDiabetes
• Prediabetic State

Intervention

Other:
• Glucose Reference 1
30 g of glucose dissolved in 250 ml of water
• Glucose Reference 2
30 g of glucose dissolved in 250 ml of water
• Glucose reference 3
30 g of glucose dissolved in 250 ml of water
• Sucrose
30 g of Sucrose dissolved in 250 ml of water
• Regular Bake beans in tomato sauce
Bake beans in tomato sauce containing 14 g of sugar
• Bake beans in tomato sauce, reduced sugar
Bake beans in tomato sauce containing 12.2 g of sugar
• Bake beans in tomato sauce, low GI
Bake beans in tomato sauce containing 7.2 g of sugar

Locations

Country	Name	City	State
Singapore	Clinical Nutrition Research Centre	Singapore

Sponsors (1)

Lead Sponsor	Collaborator
Clinical Nutrition Research Centre, Singapore

Country where clinical trial is conducted

Singapore, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Glucose [	Whole capillary blood glucose will be measure using Hemocue analyser	Up to 180 minutes
Secondary	Insulin	Capillary plasma will be measure using Cobas analyser	Up to 180 minutes