Obesity Clinical Trial
Official title:
Effects of Brisk Walking on Overweight/Obesity Population
1.Objective
The investigators aim to determine the effect of brisk walking prescription (> 10000 steps,
> five days, per week) on body components and metabolic risk factors among patients with
overweight/obesity. The objectives are as follow:
1. The body components changes before/after the brisk walking prescription (> 10000 steps,
> five days per week) intervention in overweight/obesity population;
2. The metabolic risk factors changes before/after the brisk walking prescription (<10000
steps or <five days per week) intervention in overweight/obesity population
2.Study design This study is a prospective 4-month follow-up scheme in which patients were
treated with the following intervention: > 10000 steps, > five days, per week. For
individual follow-up, body components and metabolic risk factors will be tested before and
after the study. Every participants will be followed up in community visits every month.
3. Statistical analysis Statistical analysis will be performed using SPSS 16.0 version
package (SPSS Inc., Chicago, IL.). Numerical data will be presented as mean ± standard
deviation for normal distribution or otherwise median (interquartile range). Two-sided
independent t-test is adopted for between-group comparison on end-points with normal
distribution, otherwise non-parametric test. Row-Column table will be analyzed through
chi-square test. P<0.05 is taken as statistical significant.
Obesity/overweight has been recognized as one of the most important global health threats
worldwide, which is closely related to metabolism syndrome including insulin resistance,
hypertension, dyslipidemia and hyperglycemia.
In 2013, an estimated 36.9% of men and 38.0% of women were overweight (BMI >25 kg/m2)
worldwide, with attributable fractions for CHD as high as 25% in the United States and 58%
in the Asia-Pacific Region. Furthermore, a strong and continuous association between body
mass index (BMI) and coronary heart disease (CHD) has been reported for values of BMI above
20kg/m2 .
Numerous studies have recognized the role of physical activity in promoting moderate weight
loss, weight loss maintenance, and having broad-reaching implications for cardiovascular
disease mortality indices, as well as reducing healthcare expenditures. The findings of a
recent review suggest that mild-to-moderate intensity exercises that include both aerobic
and resistance training result in additional metabolic benefits in people with obesity or
type 2 diabetes. Although weight loss is minimal, body composition improves. Brisk walking,
at an individual level, prove to be the physical activity most easy to maintain and could be
progressively increased in intensity, achieving a cardiorespiratory benefit and decrease
adiposity in the unfit.
Several small clinical trials reported inconsistent findings of short-term exercise programs
on brisk walking among patients with overweight/obesity. However, these studies did not
provide comparable indices, duration and intensity. Furthermore, the brisk walking effect of
current physical activity guidelines on obesity/overweight is uncertain.
The current study aimed to evaluate the effects of brisk walking ( > 10000 steps, > five
days, per week) on body components and metabolic risk factors among patients with
overweight/obesity.
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